6o ] 
into rats and guinea-pigs was negative and so were cultures on various 
media. 
T 1 he animal rapidly emaciated, fever continued, and ten weeks after the 
first observation and little more than three months after the first symptoms 
were noted the animal was killed. It would probably not have lived more 
than two or three weeks more. 
Post-mortem examination showed no visceral lesions and all the organs 
appeared healthy. 6 ‘ 
The vomer was covered to a great extent on both sides by areas o 
course granulation tissue raised above the surrounding mucous membranes 
affected^ ° f intense con g estion surrounded the smaller areas s< 
Sections of the subcutaneous tissues and of the growths on the vomer 
s owed masses of round celled growth. The surrounding connective tissue 
was little thickened. There was no caseation, but towards the centre of the 
larger masses the cells stain feebly and appear to be degenerate. The 
vascular supply to the growths is scanty. No organisms were found in the 
deeper parts of the growth. 
The disease appears to be closely related to if not identical with that 
described in Manila as Pseudofarcy. The resemblances to glanders are 
entirely superficial. No growths of the organism of glanders were obtained 
and injections made into animals susceptible to glanders all failed. 
No other instances occurred either in the stables occupied by other 
horses adjacent or elsewhere, and though a certain amount of care was 
exercised it would not have been sufficient to prevent the spread of any 
highly contagious disorder. J 
Malignant Disease. 
Malignant growths were noted only in Chinese. The number of 
ami Is, 3 2 > was too small for any conclusion to be drawn from the absence 
of such cases, and as no post-mortems were made on Malays no information 
is obtainable as to the frequency of inaccessible malignant growth in that 
race. 
Malignant growth was present in io cases. These post-mortems were 
in several instances selected and probably represent all or nearly all the 
cases that terminated fatally from that cause during the period under 
review. The total deaths were 805, so that the percentage of the deaths 
was not less than 1.24. 
The different age periods of deaths from all causes of those examined 
was 25 and under, 6.1 %; 30 and under, 22.1 %; 35 and under, 19.6 %, or 
50 % under 35 ; under 40, 16.8 ; 45 and under, 13.5 ; 50 and under, 8 ; 60 and 
under, 9.4; and over 60, 3.7. These ages must be received with caution 
and considered as estimates only. Accurate information is not obtainable 
and in many cases no information at all could be obtained. Of the cases of 
death from Malignant growth, 7 or 70 % were over 35, i.e., 2 over 50, 
2 o\er 45, 2 over 40, and 1 over 35, and the ages given for the other 3 were 
28, 30 and 33 respectively. 
Two 01 the cases were in persons who had been over 25 years in 
Malaya, and, therefore, must, I consider, have acquired the disease in the 
country. One had only been one year from China and possibly had not 
acquired it in this country. 
