Gf. H. Drew 
59 
nodules as secondary metastases, but this is scarcely justifiable con¬ 
sidering the impossibility of determining cytological details in 
imperfectly preserved specimens. Dr Leo Loeb, of the Pathological 
Laboratory of the University of Pennsylvania, has kindly given me his 
opinion on sections of these tumours. He considers that the growth in 
places resembles a carcinoma and in others a lipoma. He also states 
that he has occasionally observed that gland-like tumours may produce 
appearances not unlike fat tissue. 
The occurrence of Fibromata groiuing from the Opercula of 
Pleuronectes platessa. 
This condition appears to be comparatively common. I have recently 
examined five cases in which hard fibromata had developed from the 
operculum, on either surface of the fish. The tumours were extremely 
hard and closely attached to the bone, in some cases they were partially 
ossified at the base. They consisted of very compact fibrous tissue, 
often showing a somewhat laminated structure. I have been unable 
to find anything that was suggestive of the cause of this condition. 
A remarkable case of ‘ vitreous ’ degeneration in the muscles of 
Gadus aeglefinus, due to Sporozoon infection. 
This specimen showed a slight swelling following the course of the 
lateral line of each side, but otherwise appeared normal on the surface. 
On cutting into the tissue in the neighbourhood of the lateral line, it 
was found that the swelling was due to the presence of a mass of brown, 
horny looking substance, which ran along on each side, embedded in the 
muscles immediately subjacent to the lateral line. This substance was 
hard, but cut readily and smoothly with the knife; sections were semi¬ 
transparent, and appeared structureless under the microscope. The 
normal muscular tissue was not adherent to this horny mass, and 
showed no signs of inflammation even in its immediate neighbourhood : 
in fact shortly branching rods of this substance, measuring as much 
as ^ inch in diameter, and one or two inches in length, could be easily 
withdrawn, clean and without any adherent tissue. 
In places, white, pultaceous, masses of degenerated cells and fibrin 
were present, and on sectionising these masses, minute spores of some 
sporozoon, probably a species of Glugea, were made out. In the 
neighbourhood of these areas various stages of muscular degeneration 
