J. D. E. Holmes 
97 
Pony no. C 27. 270 lbs., 2nd paroxysm. 
1st day 50 c.e. atoxyl. 
3rd ,, 600 c.e. ars. ac. sol. 
4th „ 1 gm. ars. ac. 
6th ,, 50 c.e. atoxyl. 
8th ,, 500 c.c. ars. ac. sol. 
13th day of disease. 
9th day 1 gm. ars. ac. 
11th ,, 50 c.c. atoxyl. 
13th ,, 500 c.c. ars. ac. sol. 
14th ,, 1 gm. ars. ac. 
This pony was treated on a different system. The arsenious acid 
solution and arsenious acid were given on consecutive days and the 
atoxyl alternately, after one day interval. 
No return of trypanosomes. Kept under observation 9 months. 
Three other ponies, treated in the same method, showed a return of 
the disease a few days after treatment ceased. 
Pony no. 94. 300 lbs., 2nd paroxysm. 
1st day 300 c.e. ars. ac. sol. 
2nd „ 50 c.c. atoxyl. 
3rd ,, 1 gm. ars. ac. 
Four days interval. 
8th day 300 c.c. ars. ac. sol. 
9th ,, 50 c.c. atoxyl. 
13th day of disease. 
10th day 1 gm. ars. ac. 
Eight days interval. 
19th day 300 c.c. ars. ac. sol. 
20th ,, 50 c.c. atoxyl. 
21st ,, 1 gm. ars. ae. 
4th day of disease. 
10th day 1 gm. ars. ac. 
Eight days interval. 
19th ,, 300 c.c. ars. ac. sol. 
20th ,, 25 c.c. atoxyl. 
21st ,, 1 gm. ars. ac. 
Trypanosomes reappeared 30 days after last dose. 
Pony no. 95. 300 lbs., 1st paroxysm. 
1st day 300 c.c. ars. ac. sol. 
2nd ,, 25 c.c. atoxyl. 
3rd ,, 1 gm. ars. ac. 
Four days interval. 
8th day 300 c.c. ars. ac. sol. 
9th ,, 25 c.c. atoxyl. 
Trypanosomes reappeared 14 days after last dose. 
Pony no. 96. 230 lbs., 1st paroxysm. 
1st day 300 c.c. ars. ac. sol. 
2nd ,, 30 c.c. atoxyl. 
3rd „ 1 gm. ars. ac. 
Four days interval. 
8th day 300 c.c. ars. ae. sol. 
9th ,, 30 c.c. atoxyl. 
4th day of disease. 
10th day 1 gm. ars. ae. 
Eight days interval. 
19th day 300 c.c. ars. ac. sol. 
20th ,, 30 c.c. atoxyl. 
21st „ 1 gm. ars. ac. 
Trypanosomes reappeared 7 weeks after last dose. 
Pony no. 97. 320 lbs., 3rd paroxysm, 
other treatment without success. 
21st day of disease. This pony had received 
14th day 50 c.c. atoxyl. 
15th ,, 1 gm. ars. ac. 
Twelve days interval. 
28th day 400 c.c. ars. ac. sol. 
29th ,, 50 c.c. atoxyl. 
30th ,, 1 gm. ars. ac. 
1st day 50 c.c. atoxyl. 
4th ,, 300 c.c. ars. ac. sol. 
5th ,, 50 c.c. atoxyl. 
6th ,, 1 gm. ars. ac. 
Six days interval. 
13th day 300 c.c. ars. ac. sol. 
Trypanosomes reappeared 12 days after last dose. 
Parasitology hi 
