98 
Surra 
Treatment with Soamin. 
Effect of a single dose. 
Pony no. 98. 
subcutaneously. 
350 lbs., 1st paroxysm. 2nd day of disease. 60 c.c. of 4 °/ 0 soamin 
Trypanosomes disappeared from the circulation for nine days. 
Pony no. 99. 
subcutaneously. 
407 lbs., 1st paroxysm. 3rd day of disease. 60 c.c. of 4 °/ 0 soamin 
Trypanosomes disappeared from the circulation for six days. 
Mule no. 100. 
subcutaneously. 
500 lbs., 1st paroxysm. 2nd day of disease. 100 c.c. of 4 °/ 0 soamin 
Trypanosomes disappeared from the circulation for 12 days. 
Pony no. 101. 
subcutaneously. 
250 lbs., 1st paroxysm. 4th day of disease. 
Pony died the following day. 
100 c.c. of 4 °/ 0 soamin 
Pony no. C 31. 250 lbs., 3rd paroxysm. 22nd day of disease. 100 c.c. of 10 °/ 0 
soamin subcutaneously. The pony was off feed and unable to rise for several days after 
which he gradually recovered. No reappearance of trypanosomes. Kept under observa¬ 
tion 8J months. 
Pony no. 102. 298 lbs., 2nd paroxysm. 12th day of disease. 
1st day 50 c.c. of 4 °/ 0 soamin. 
3rd ,, ,, ,, 
5th ,, ,, ,, 
7th 
Pony was off feed and treatment was discontinued. Trypanosomes reappeared 14 days 
after last dose. 
Soamin administered by the mouth in large doses (20 gms. per 
500 lbs.) had no effect on the trypanosomes in the blood. Continuous 
treatment by the same method had no influence on the course of the 
disease. 
Treatment with Mercury. 
Mercury alone. 
Pony no. 103. 340 lbs., 1st paroxysm. 3rd day of disease. Received 50 c.c. HgCl 2 
(1 in 1000) subcutaneously. Trypanosomes disappeared after the first dose but reappeared 
the following day and remained in the circulation for three days. The treatment was 
continued, the pony received 50 c.c. HgCl 2 (1 in 1000) for four consecutive days, followed 
by 20 c.c. intravenously for 12 days. 
Trypanosomes reappeared 8 days after the treatment ceased. They 
were absent during the second period of treatment. 
Pony no. 104. 560 lbs. A spontaneous case received for treatment in an advanced 
stage of the disease. Received three injections daily of 50 c.c. HgCl 2 (1 in 1000) followed 
by five injections daily of 35 c.c. 
Trypanosomes reappeared in the circulation 4 days after treatment 
ceased. They were absent during the period of treatment. 
