104 
Surra 
A summary showing the comparative value of the preparations experi¬ 
mented with in clearing the peripheral circulation from trypanosomes. 
A single dose of each preparation was given when the trypanosomes 
were numerous in the blood and on the 1st or 2nd day of paroxysm. 
Except where otherwise stated, the parasites were absent from the 
circulation the day following the administration of the dose. 
The effect of the drug was estimated by the period during which the 
blood remained free from trypanosomes. 
Atoxyl. 
No. of 
animal 
Weight 
in lbs. 
Amount of drug 
Method ad¬ 
ministered 
Periods 
Pony 
127 
250 
30 c.c. of 4 °/ 0 
subcutaneous 
9 days 
9 9 
128 
280 
30 
9 9 
7 „ 
99 
129 
350 
200 „ (arsacetin) 
99 
Cured 8J months 
99 
130 
300 
100 c.c. of 2 % 
99 
4 days 
99 
99 
300 
150 
99 
6 „ 
99 
99 
300 
200 „ 
99 
7 „ 
Mule 
131 
450 
100 
99 
6 „ 
99 
99 
450 
200 „ 
99 
7 „ 
9 9 
132 
500 
100 
99 
3 „ 
99 
9 9 
500 
150 
99 
5 „ 
9 9 
9 9 
500 
200 
99 
8 „ 
99 
133 
600 
40 c.c. of 4 °/ 0 
intravenous 
6 ,, 
Pony 
134 
660 
50 „ 12 
J 9 
5 i. 
9 9 
135 
300 
4-8 gms. 
by mouth 
No effect 
9 9 
136 
229 
3-0 „ 
»» 
99 
9 9 
137 
300 
6-0 „ 
99 
Died in 17 hrs. 
Soamin. 
Mule 
138 
550 
100 c.c. 
o 
o 
O 
H 
O 
subcutaneous 
12 days 
9 9 
139 
530 
100 
4 
99 
6 „ 
Pony 
140 
350 
60 
99 
99 
No effect 
9 9 
141 
407 
60 
9 
99 
99 
99 
C 31 
250 
100 
, io% 
99 
Cured 8| months 
9 9 
143 
550 
100 
„ 4 
intravenous 
No effect 
9 9 
144 
250 
3 - 0 gms. 
by mouth 
99 
9 9 
99 
250 
5-0 „ 
9 9 
9 9 
9 9 
99 
250 
6-0 „ 
9 9 
9 9 
9 9 
145 
260 
100 „ 
9 9 
13 days 
