30 
Pliysaloptera Praeputialis 
formed a segment of a circle, others were cone-shaped, others again had 
the appearance of an elongated cone and at the tip of the cone there 
was sometimes a “pin-point” orifice. All the swellings were uniformly 
hard and anaemic; their borders were well-defined, and they appeared 
to be seated in the muscular structures. The overlying serosa was not 
the seat of any exudative process; there was a little thickening of the 
subendothelial tissues but there were no signs of adhesions. The 
process showed the signs of chronicity and was apparently enterogenous 
in origin. 
When the stomach and intestines were opened up, similar nodules 
projected into the lumen of the canal. In this case they were 
covered by the mucosa; at or about the centre of the raised area, how¬ 
ever, the mucous coat was deficient, leaving an aperture which 
communicated with the interior of the nodule. 
In the stomach the nodules were few in number but large in size; 
in the small intestines they were more numerous, of medium size, and 
subserous rather than submucous; in the large intestine there were 
so many that they practically occupied the entire area, being separated 
from one another by a small area of lymphoid tissue only. 
The whole alimentary tract was in a condition of advanced 
catarrhal inflammation, and iu the lumen large numbers of the worms 
were present. 
When the nodules were bisected, they were found to consist of dense 
fibrous tissue surrounding an irregularly branching lumen. In the 
lumen a number of small worms were seen. Microscopical examination 
showed that each of the young worms was surrounded by bands of very 
dense fibrous tissue, and that the fibrosis was less marked towards the 
periphery of the mass; the peri-nodal tissues showed but slight 
proliferative changes. 
The general appearances suggested that the female worm burrowed 
through the mucosa and deposited embryos in the submucosal tissues. 
During the development of the worms a fibrous nodule was formed, and 
the nodule extended into the muscular layer causing considerable 
atrophy of the muscle fibres, and in some cases reached the subserous 
tissues. In the latter instance, when the young worm happened to lie 
immediately beneath the serosa or was cut off from the intestinal 
aperture by fibrous tissue, it commenced to burrow and so reached 
intraperitoneal organs, such as the liver and spleen. When, however, 
the worm was in a position to utilize the opening into the alimentary 
canal it emerged from the nodule, buried its head in mucosal tissue and 
