W. S. Patton 
95 
of the habitat of trypanosomes in an invertebrate host. We will 
criticise Schaudinn’s observations in this connection further on. 
Provvazek’s (1905) work on the development of T. lewisi in Haemato- 
pinus spinulosus is next described and the migrations of the so-called 
developmental forms of T. lewisi in the louse are said to agree in the 
main with Schaudinn’s observations. Mammalian trypanosomes however 
have so far only been found in the alimentary tracts of tsetse dies; 
but Koch believes that the flagellates he found in the salivary glands 
of certain Glossinae are identical with T. gambiense. This is however 
by no means proved. 
Woodcock next refers to Brumpt’s (1906) work on the development 
of piscine trypanosomes in leeches, and notes that they also are restricted 
to the alimentary tracts of these invertebrates; in a footnote Brumpt’s 
(1907) later observations on the hereditary transmission of certain 
leech trypanosomes are mentioned. According to Brumpt three kinds 
of behaviour of trypanosomes in leeches can be distinguished, (a) The 
parasites develop solely in the stomach of the leech and never pass into 
the intestine or sheath of the proboscis; this is the method of develop¬ 
ment of T. remalci. (b) In the case of T. granulosum the development 
begins in the stomach of the leech and is continued in the intestine, 
where the parasites may remain for a long time; they then pass back 
again to the stomach and later to the proboscis sheath, (c) This 
method of development goes on in the stomach, the parasites, T. dani- 
lewstcyi, in time finding their way back to the sheath of the proboscis. 
T. raiae and T. scylli, which, according to Brumpt, develop in 
Pontobdella, undergo their evolution in the stomach and intestine of 
the leech, but Brumpt was unable to ascertain how they passed back 
again into the fish. Miss Robertson (1907) has recently described what 
she considers to be the development of T. raiae in Pontobdella muricata. 
We shall criticise these views regarding developmental cycles of piscine 
trypanosomes in the section dealing with the life histories of these 
parasites. 
With regard to the effect of trypanosomes on vertebrate hosts, 
Woodcock gives a short resume of the train of events in an infection 
with one of these parasites. We note however that Salvin-Moore and 
Breinl’s (1907—08) recent work on T. gambiense, T. equiperdum and 
T. lewisi is only just referred to. We consider this work should have 
been described in detail. Woodcock draws attention to the great 
variation in the size and shape exhibited by many trypanosomes and 
states that in some instances at any rate sexual differentiation is 
