158 
The Cure of Piroplasmosis 
We herewith subjoin the protocols of two experiments with these 
drugs: 
Arsacetin Experiment. 
Day 
1. Bog: Inoculated with 5 c.c. of defibrinated heart blood. 
5. Parasites appeared. 
Treatment begun : 2 c.c. of 5 °/ 0 arsacetin dissolved in water injected sub¬ 
cutaneously. 
7. Treated as before, dog looking very ill, parasites increasing in numbers; haemo- 
globinuria. 
8. Dog died of piroplasmosis. 
Control dog died on 9th day. 
Result: The treated dog died on 8th day, the control dog died on 9th day. 
Soamin Experiment. 
Day 
1. Dog: Inoculated with 5 c.c. of defibrinated heart blood. 
5. Parasites appeared. 
Treatment begun: 1-5 c.c. of 1 °/ 0 soamin dissolved in water injected sub¬ 
cutaneously. 
6. Fifteen parasites per field. 
7. Treated as before, many parasites in blood. 
8. Dog ill. 
9. Dog died. 
Control dog died on 8th day. 
Result: The treated dog died on 9th day, the control dog died on 8th day. 
Note to Diagram on p. 159. 
Fig. 1 represents the entrance of a free pyriform parasite into a fresh corpuscle. The 
parasite retains its pyriform shape for a short time after it has effected an entrance 
into the corpuscle. The presence of single intracorpuscular pyriform parasites is 
indicated by the sign (P) in our protocols. 
Figs. 2—7 represent successive stages of development: the pyriform parasite becomes 
rounded, grows in size, becomes amoeboid and undergoes nuclear changes of a peculiar 
character prior to the protrusion of the bud-like processes, as shown in Fig. 8. Such 
forms are all grouped under the sign (0) in our protocols. 
Figs. 8—12 represent successive stages of development from the first protrusion of the 
“ buds ” to the almost completely formed pair of pyriform parasites. Such forms are 
all grouped as dividing forms under the sign (D) in the protocols. This stage is short¬ 
lived. 
Figs. 13—14 represent the completely formed pair of pyriform parasites, at first conjoined 
[13] and then separated [14] from each other. Such forms are grouped under the sign 
(PP) in the protocols. 
Fig. 15 represents the escape of the pyriform parasites from the corpuscle and their almost 
immediate entry into fresh corpuscles, as seen in Fig. 1. 
