168 
The Cure of Piroplasmosis 
reason that only a few infected corpuscles could be detected at the edge 
of the film. In the fifth column the time is stated when the parasites 
could no longer be detected in blood films by microscopic observation. 
TABLE I. 
Dose of drug 
given per oz. 
of dog, c.c. of 
sat. solution 
% of infected r.b.c. 
Time it took for 
all parasites to 
disappear after 
drug injection 
Dog 
No. and description 
At time 
when drug 
was given 
> 
At stated inter¬ 
vals of time after 
drug was given 
Remarks 
2. 
Collie: § grown, 
wt. 20 lbs. 
•012 TR. 
6 
? after 70 hrs. 
96 hrs. 
Advanced ease, died. 
3. 
Terrier: adult, 
wt. 17i lbs. 
•01G TB. 
0-2 
? after 6 hrs. 
22 hrs. 
Recovered. 
4. 
Terrier: adult, 
wt. 20 lbs. 
•017 TB. 
3-4 
1-2 after 3 hrs. 
47 hrs. 
Recovered. 
9. 
Terrier: pup, 
wt. 7 lbs. 
•032 TB. 
v. few 
? after 6 hrs. 
42 hrs. 
Recovered. 
10. 
11. 
Terrier: pup, 
wt. 1 lb. 11 oz. 
Terrier: pup, 
•037 TB. 
•037 TB. 
4-5 
3-8 
2-7 after 9 hrs. 
1’4 after 7 hrs. 
20 hrs. ' 
- 
20 hrs. 
Both died from re¬ 
lapse. See note to 
protocols on p. 186. 
wt. 1 lb. 4 oz. 
Dog 2 was treated in an advanced stage of the disease on the 6th 
day after the parasites had appeared, and when 6 °/o °f the red blood cor¬ 
puscles were infected. This dog ultimately died, but no parasites could 
be found in its body at autopsy. Dogs 3, 4 and 9 received treatment 
24—25 hours after the parasites first appeared in their blood; all three 
recovered. Dogs 10 and 11 were inoculated on the same day when the 
parasites first apjpeargd in their blood ; they died of piroplasmosis. 
If we summarize the effect of the drug in causing the disappearance 
of the (PP) parasites alone we find the following results were obtained, the 
percentage of (PP) parasites being reckoned in terms of the percentage of 
(O) parasites, as stated on page 161. 
TABLE II. 
The % of (PP) parasites in blood-films 
Dog No. 
At time 
when drug 
was given 
Reduction at stated 
intervals of time 
after drug was given 
Time when all 
(PP) parasites disappeared 
2* 
40 
9 after 70 hrs. 
96 hrs., advanced case. 
3 
62 
0 after 6 hrs. 
6 hrs., recovered. 
4 
69 
1 after 3 hrs. 
11 hrs., recovered. 
9 
125 
2 after 6 hrs. 
20 hrs., recovered. 
10 
78 
2 after 9 hrs. 
21 hrs., died. 
11 
125 
3-7 after 7 hrs. 
9 hrs., died. 
* TR. treated. 
