G. H. F. Nutt all and S. Hadwen 
179 
Dog 5. 
Adult Fox terrier. Weight 13| lbs. Beceived one dose of the drug. 
(7. iv. 09.) 
(13. v. 09.) 
Day 
Temp 
•F. 
1. 
— 
Inoculated with 6 c.c. of heart blood. 
4. 
— 
Parasites appeared: 3 infected r.b.c.: 2 (PP), 1 (O) at film-edge. 
5. 
101-0. 
0'4 °/ 0 of r.b.c. infected (500 counted). 
6. 
104-7. 
Treatment: 5 c.c. of sat. sol. Trypanblau at mid-day. Dog 
became very blue. 
2 infected r.b.c. found at film-edge (10 a.m.). Swelling at seat 
7. 
101-2. 
of drug injection. 
No parasites. Dog lively; swelling lanced, sero-pus escaping. 
8. 
101-5. 
,, ,, ,, ,, diminishing. 
9. 
101-0. 
„ „ „ ,, practically gone. 
10. 
102-2. 
ii ii 
11. 
101-6. 
i ) ii 
12. 
102-0. 
ii if 
13. 
101-7. 
f i ii 
14. 
103 0. 
,, ,, Dog weighed 12 J lbs. 
15. 
102-7. 
ii ii 
16. 
1011. 
3 infected r.b.c. found at film-edge: 2 (PP), 1 (O). 
17. 
101-8. 
No parasites. 
18. 
101-8. 
ii a 
19. 
101-8. 
a a 
20. 
101-5. 
a a 
21. 
101-7. 
i i a 
22. 
102-7. 
5 infected r.b.c. at film-edge: 3 (PP), 2 (O). 
23. 
101-9. 
8 „ „ „ 7 (PP), 1 (O). 
24. 
101-0. 
3 „ „ „ 3 (PP). 
25. 
100-9. 
6 ,, „ „ 5 (PP), 1 (O). 
26. 
101-3. 
5 „ „ „ 4 (PP), 1 (O). 
27. 
103-0. 
No parasites. 
28. 
102-0. 
1 infected r.b.c. at film-edge: 1 (PP). 
29. 
Normal. No parasites. 
30. 
101-2. 
ii H 
31. 
100-8. 
a a 
32. 
1010. 
a a 
36. 
101-0. 
a a 
38. 
102-4. 
a a 
After this date rises of temperature were recorded on the 42nd (103'2° F.), 
45th (106°), 46th (104°), and 58th (103-4°) days. Parasites were only dis¬ 
covered once at the edge of a blood film, 2 (O), on the 56th day, after which 
they could no longer be detected. On the 4‘2nd day the dog weighed 13J lbs. 
On the 57th day severe mange set in and the animal rapidly became ill and 
emaciated. On the 67th day it developed distemper with copious discharges 
from the nose and eyes. The dog died of distemper and mange on the 69th 
day, its weight having fallen to 7J lbs. No Piroplasma could be found at 
autopsy (14. vi. 09). 
Note :—Dog not examined on days 33, 34, 35, 37. 
Control Dog Y (see p. 170) died on the 9th day after inoculation. 
12—2 
