229 
FURTHER EXPERIMENTS UPON THE DRUG 
TREATMENT OF CANINE PIROPLASMOSIS 
By GEORGE H. F. NUTTALL, M.D., Ph.D., Sc.D., F.R.S., 
Quick Professor of Biology , Cambridge , 
AND S. HADWEN, D.V.Sc. (McGill), 
First Assistant Pathologist, Health of Animals Branch , Department of 
Agriculture , Canada. 
CONTENTS. 
PAGE 
Preventive treatment with Trypanblau.229 
Experiments with Trypanblau given by the mouth .... 231 
Experiments with Tryparosan ......... 233 
Summary and Conclusions.234 
Preventive Treatment with Trypanblau. 
In our previous paper (vi. 1909, p. 187) we described an experiment 
in which a dog (No. 13) was inoculated with virulent blood and on the 
day following received an injection of trypanblau subcutaneously. This 
dog showed no parasites, although its blood was examined almost daily 
up to the 49th day after inoculation. A control dog, on the other hand, 
died on the 7th day after inoculation. 
The result of this experiment was so striking that we determined to 
repeat it, using a number of dogs for the purpose so as to exclude any 
possible error. 
The following experiments were carried out on nine dogs, all of 
which were inoculated (23. IV. 1909) with defibrinated heart-blood taken 
from a dog which was killed whilst moribund from piroplasmosis. Two 
of the nine dogs served as controls. 
