J. D. E. Holmes 
299 
Pony C 57. 550 lbs. 
1st day 600 c.c. ars. ac. sol. 8th day 800 c.c. ars. ac. sol. 
2nd ,, 60 c.c. atoxyl. 9th „ 60 c.c. atoxyl. 
3rd ,, 1‘5 gins. ars. ac. 10th ,, 2 gms. ars. ac. 
Four days interval. 
No further treatment was given as the animal showed symptoms 
of poisoning after last dose and remained dull and off feed for several 
days. 
No return of trypanosomes. Kept under observation 3 months. 
Pony C 58. 460 lbs. 
1st day 600 c.c. ars. ac. sol. 
2nd ,, 60 c.c. atoxyl. 
3rd ,, 1-5 gms. ars. ac. 
Four days interval. 
8th day 800 c.c. ars. ac. sol. 
9th ,, 60 c.c. atoxyl. 
10th ,, 2 gms. ars. ac. 
The pony showed symptoms of poisoning and was dull and off feed 
for several days. Treatment was suspended. Trypanosomes reappeared 
in the circulation 23 days after last dose. The animal was then put on 
treatment with atoxyl and arsenic in alternate doses. 
1st day 60 c.c. atoxyl. 
3rd ,, 1 gm. ars. ac. 
5th ,, 60 c.c. atoxyl. 
7th ,, 1'5 gms. ars. ac, 
9th day 60 c.c. atoxyl. 
11th ,, 2 gms. ars. ac. 
13th ,, 60 c.c. atoxyl. 
15th ,, 2 gms. ars. ac. 
No return of trypanosomes. Kept under observation 3 months. 
Pony C 59. 540 lbs. 
1st day 600 c.c. ars. ac. sol. 
2nd ,, 60 c.c. atoxyl. 
3rd ,, l - 5 gms. ars. ac. 
Four days interval. 
8tli day 800 c.c. ars. ac. sol. 
9th ,, 60 c.c. atoxyl. 
10th ,, 2 gms. ars. ac. 
The pony showed symptoms of poisoning and was dull and off feed 
for four days. Treatment was suspended for 25 days. No relapse 
occurred, but as there was a doubt whether a cure had been effected 
the animal was put on a course of atoxyl and arsenic in alternate 
doses. 
1st day 60 c.c. atoxyl. 
3rd ,, l - 5 gms. ars. ac. 
5th ,, 60 c.c. atoxyl. 
7tli ,, 1-5 gms. ars. ac. 
9th ,, 60 c.c. atoxyl. 
11th day 2 gms. ars. ac. 
13th ,, 60 c.c. atoxyl. 
15th ,, 2 gms. ars. ac. 
17th ,, 60 c.c. atoxyl. 
19th ,, 2 gms. ars. ac. 
No return of trypanosomes. Kept under observation 3 months. 
