AND REMARKS ON THAT DISEASE. 
343 
however, it is to be remembered that remissions, and even inter¬ 
missions, have occasionally been observed in the disease, both 
when nothing has been done, and when various other remedies 
have been given. I must here express my gratification at the 
conduct of Mr. Caesar Hawkins in supplying us with some ex¬ 
tract which he had in his possession after the juice sent from the 
College was exhausted. The article is very scarce. Attached to 
another school, and himself engaged in experiments with the re¬ 
medy, he showed no desire to keep the chance of successful in¬ 
vestigation to himself, but the desire of a man of science and 
benevolence to further it, whosoever might reap the credit. The 
close attention of the students both night and to the case in 
furthering the exertions of Dr. Roots, who vsuod the patient 
early in the morning, at noon, and at night, was also in the 
highest degree praiseworthy. They did so at some personal risk, 
for the boy, in his rage, more than once attempted to bite, to say 
nothing of his general violence. Some had his saliva on their 
hands, and one, I believe, got it in his eye: even the gentleman 
who opened the body was unfortunate enough to wound himself; 
and I saw the wrist of the sister of the ward bleeding, so se¬ 
verely was it scratched by the boy in his efforts to prevent her 
from administering an injection. 
The muscles of the tongue and lower jaw of the dog were nearly 
. paralysed, and the breathing was accompanied by a hoarse and 
grating sound. The true rabid howl was frequently uttered, and 
the dog was restless to a very great degree. One dose was given 
(about half an ounce of the expressed juice of the guaco) in the 
afternoon, and the second in the evening, with some slight relief 
of the symptoms; but, after the third dose, on the following 
morning, the change was most extraordinary. The dog recovered 
to a very considerable degree the use of the jaw, and could not 
only masticate the food when put into his mouth, but could with 
tolerable ease pick it from the floor: the howl ceased, and the 
restlessness disappeared. I had witnessed much mitigation of 
symptoms from the belladonna, alisma plantago, and Scutel¬ 
laria, but nothing to this extent. I was surprised and pleased, 
and almost began to fancy, that at length the grand specific was 
discovered. The medicine was continued during the day, but on 
the following morning the dog was found nearly paralysed all over, 
and died. The remission of the symptoms was very extraor¬ 
dinary, and the medicine deserves farther trial. Mr. Hawkins 
will doubtless favour the medical world with a detailed account of 
the experiment. 
