380 
ON GLANDERS. 
it is deposited, &c. 2cc. &c. Garsault adds, that when strangles 
has not been radically cured in the colt, it returns in a more 
dangerous form, receiving then the appellation of bastard strangles , 
which runs into expectoration, and that degenerates into pul¬ 
monary consumption: the horse then dies of what is called 
glanders, an incurable disease. From an observation of Gar- 
sault’s, M. Dupuy finds, that the practice of killing glandered 
horses has long existed; and yet, he remarks, the number 
affected continues undiminished: a circumstance he adduces to 
show the inefficaciousness of this expedient, and one, he adds, 
that ought to induce government to adopt some other measure 
more conformable to observation and experience, and conciliatory 
to the interests of the community. 
The seat of glanders formed the principal object of research of 
Lafosse senior ; he attached the greatest importance to this dis¬ 
covery : it constituted the foundation of his medical system. 
“Authors who have hitherto written on glanders,” says his son, 
“ have been equally unacquainted with its seat and remedy. This 
malady has been referred by some to the brain, by others to the 
lungs, to the liver, to the kidneys, who, confounding the diffe¬ 
rent defluxions, have given the name of glanders to all such as 
were nasal. My father, to whom the light of hippotomy exposed 
the ridiculous errors of the farriers, betook himself in the year 
1741 to the research of its veritable seat. In the end, he dis¬ 
covered this to be, in 1749, the pituitary membrane, and pub¬ 
lished his discovery in a memoir which he presented to the Royal 
Academy of Sciences. The report of the commissaries, Messrs. 
Bouvard and Meripant, confirmed this truth. Ever instigated by 
the love of his profession and the public weal, he pursued his in¬ 
vestigations until he was enabled to distinguish the different nasal 
discharges : he recognised seven different kinds, and showed, in 
1751, in a supplement to his original memoir, that only one of 
them deserved the name of glanders; a fact that was also con¬ 
firmed in another report of the commissaries of the Academy, 
Moraud and Bouvard.” 
Convinced of the local nature of glanders, Lafosse set about 
producing it, not by communication, but by artificial means, as the 
injection of corrosive liquors; and affirms that he has often seen 
it supervene upon mechanical nasal injuries: he therefore rejects 
all constitutional aid. Comparing it to ozena in man, he insists 
upon the efficacy of topical agents alone, such as fumigations, 
detersive injections, the trepan, &c. He avows, however, that 
his success was not uninterrupted. 
Jealous of upholding the fame of his father, Lafosse junior 
addressed a dissertation to the Academy of Sciences, in which lie 
