ON GLANDERS. 
undertook to remove existing doubts, and to prove, by fresh ex¬ 
periments, that glanders had its existence (exclusively) in the 
pituitary membrane. It was only required to have eyes, he said, 
to be convinced of this truth. After all, however, he achieved 
nothing in addition to what his father had already done, and left 
the nature of the affection undeveloped : and, indeed, it is clear, 
by the report, that his father’s memoir did not receive the general 
approbation of the Academy, as was triumphantly asserted by 
young Lafosse, for there were distinguished individuals who still 
maintained the humoral pathology. 
Malouin was one of those who was not a convert to the doc¬ 
trine of Lafosse and his son. He had frequent opportunities of 
examining glandered subjects, and the pathological results of his 
observations were,—That the brain was healthy; the membrane 
of the nose redder, thicker, and looser in texture than in the 
healthy state, more or less besmeared with matter resembling 
what had been ejected before death, and entirely or partially vi¬ 
tiated ; and that the velum palati also was often similarly affect¬ 
ed. Impressed with, these notions, M. Malouin obtained the 
assent and concurrence of the superintendants of the king’s 
stables, to subject several glandered horses to treatment, consist¬ 
ing of long-continued periodical purgations, the administration of 
antimony in combination with mercury, nasal injections and fu¬ 
migations, trepanning the sinuses, incising and potentially cau¬ 
terizing the submaxillary tumors, &c. &c., but all proved to be 
of no avail; for, though there were horses that recovered under 
such treatment, others fell victims to the disease whose cases pre¬ 
sented equal hopes of success. 
Glanders, says Paulet, is a malady, the cure of which has 
proved, to the present day, a stumbling-block to those engaged 
in the hippiatric art: the difficulty of stamping its character, and 
of establishing its true seat, is scarcely exceeded by that of re¬ 
moving it. He argues the indispensable necessity of a rigorous 
definition of its nature to guide us in our prognosis, lest we con¬ 
found it with other nasal fluxions; and cites the works of M. M. 
Lafosse, Malouin, Moraud, and Jenon, as the best sources of 
this useful information. In order to have a correct idea of glan¬ 
ders, Malouin says he must compare it to syphilis; the two 
poisons exert their influence in the same way; in both diseases 
the presence of virus contaminates the lymphatic fluids, and thus 
infects the neighbouring glands. Following up this opinion, as 
there was known a remedy for the one, Malouin undertook to 
furnish a specific for the other. Accordingly, in the year J759, 
experiments were made by him upon several horses belonging to 
the king. This work contains observations on different fluxions 
