FOR THg CURE OF GLANDERS. 
529 
I am disposed to believe that the analogy which exists between 
chlorine and iodine, extends not only to the chemical properties 
of these two elementary bodies, but also to their medicinal effects. 
And it will, therefore, be convenient to place in our pharmacolo¬ 
gical tables, chlorine and its preparations by- the side of iodine, 
and the medicines of which it forms the base. 
The Effect of the Injection of certain Medicines 
into tiie Veins. 
By M . Dupuy. 
[Journal Pratique, June 1830.] 
After having remarked that the accounts we have of the 
action on the quadruped, of most of the drugs used in human 
medicine, are either conjectural or false, or founded on doubtful 
observations, experiments badly conducted, with improper doses, 
or indications of disease most unskilfully appreciated; and that, 
in point of fact, the greater part of the medicaments usually resorted 
to are perfectly inert w 7 hen administered in small doses, and 
dangerous when given in greater quantities, and that we are 
almost destitute of arms with which to contend against too many 
of the maladies of our patients ; M. Dupuy is anxious that their 
effect should be ascertained when administered in some other way 
than by the mouth. He has, therefore, instituted a course of 
experiments on their power when injected into the jugular vein. 
The account of the commencement of these experiments is far 
from being so scientific as we could have wished, or as we should 
have expected from the Director of the veterinary school atToulouse, 
but much useful information is to be obtained from it. We 
translate his narrative, somewdiat abbreviated. 
On the 23d of March, at 8 o’clock in the morning, we injected 
into the jugular vein of a Hungary horse, twelve years old, and 
which was condemned on account of glanders, six grains of 
tartarized antimony, dissolved in a pint of w T ater, and at the 
temperature of 28 (95 Fah.) degrees. We presently observed 
frequentyawnings, and attempts to vomit, followed by acceleration 
of the pulse and of respiration, and afterwards a copious evacuation 
of white-coloured urine. The effect lasted only a few hours. 
On the following day the same quantity was injected, and pro¬ 
duced the same results, but an oedematous swelling, which before 
these injections had existed at the sheath, and extended under 
the abdomen, had very much diminished, and the discharge 
from the nostrils had increased and become bloody. 
A third injection, and of the same quantity, was tiied two days 
afterwards, and which produced convulsive movements of the 
muscles of all the limbs. The animal voided his mine every 
vol. in. 4 b 
