596 ON THE EFFECT OF CERTAIN MEDICINES 
Four ounces of senna infused in a pint of water, were given to 
a sheep three years old. No purging ensued, but the animal 
died fifteen days afterwards, and the last stomach and the intes¬ 
tines generally were very much inflamed. 
Two ounces of aloes made into balls, were given to a sheep 
eight years old. It died seventeen days afterwards without 
having been purged. 
Bourgelat has recorded the following experiments:—* 
Twenty-two grains of tartarized antimony produced no effect 
upon a sheep. They were given in divided doses. The animal 
had been kept twelve hours without eating. Ten grains of the 
emetic tartar were then administered. Two hours afterwards 
he was drenched with w T arm water, which instead of nauseating 
the animal, seemed to reanimate him. At the expiration of another 
hour four grains more w ere given, and the remaining eight grains 
at intervals of half an hcur. No effect w r as perceived but a co¬ 
pious flow of limpid urine, as in the natural state of the animal. 
Two drachms of tartarized antimony w r ere given at eight o'clock 
in the morning to a strong mule: they excited in her for about 
an hour violent heaving’ of the flanks, and rumbling of the 
bow r els; but she continued to eat, and dunged and urined as 
usual. 
At ten o’clock four drachms w r ere given to her in an infusion 
of an ounce of senna. At the moment of administering the 
drink, she dunged, and the dung was of its natural state. Some 
minutes afterwards, she voided dung of less consistence, and her 
urine w r as as thick and white as milk. At eleven o’clock she 
passed a very loose stool, and did not dung afterw r ards during 
the day, but she voided urine frequently, and always as w r hite 
and thick as before. 
On the following morning two drachms more w r ere adminis¬ 
tered. This excited no beating of the flanks, but she snorted 
considerably in the morning, and from three o’clock until six she 
passed much urine, thick and white as on the preceding day. 
She was likew ise purged ten times. 
On the next day an ounce of the tartar emetic was given, and 
two hours afterwards, as was also done in the former experiments, 
she w as drenched w ith a considerable quantity of w^arm w ater 
She snorted and sneezed very much, urined often, thick and 
white as before, was purged ten or twelve times, and seemed 
much distressed. 
A day’s repose was now given to her, when two ounces of 
emetic tartar w r ere administered. No sensible effect w as pro¬ 
duced, except that she staled often, the urine was less thick and 
white, and she neither snorted nor purged. 
