ON GLANDERS IN MAN, &C. 379 
leave no doubt as to the possibility of transmitting glanders to 
man, to the dog, to the ox, to the sheep, and to other animals. 
The comparative study of glanders in the different species 
shews that all are not equally apt to contract this disease, and that 
it is much more frequent in the horse than in any other domes¬ 
ticated animal. In him alone the spontaneous development of the 
disease has been observed; and among the horse tribe this disease 
may be propagated by inoculation, by contagion, and by infection. 
The spontaneous development of glanders, and its transmission 
by infection, have not yet been observed in the ruminant; but both 
the ox and the sheep have been fatally inoculated with the virus. 
The dog, among the carnivorous animals, is in precisely the same 
situation. He inhabits with impunity the stables in which there 
are glandered horses; but he may contract glanders by inoculation 
with the virus of glanders, and there are strong reasons for believ¬ 
ing that it may be developed in him, in consequence of the applica¬ 
tion of the matter of glanders coming from the horse or the ass, 
and lodged upon a mucous membrane; and also by living in stables 
in which many glandered horses are collected. Every individual 
in which we have seen the development of glanders has by his 
profession, qr his course of study, been in frequent connexion with 
glandered or farcied horses. They were either grooms, or pupils, 
or veterinary surgeons. 
The spontaneous development of certain diseases, in many 
animals, and from which others are exempt, except these diseases 
are communicated to them by contagion, is a very remarkable fact. 
There are certain morbid poisons which are never spontaneously 
produced in the human being—such are madness, so frequent in 
the dog—the malignant pustule often observed among ruminants, 
and such, in fine, is glanders, the spontaneous development of 
which is not rare among the soli pedes: but, unfortunately, man, 
under certain conditions, is apt to absorb these morbid poisons, and 
to experience all their effects, and all their intensity. 
This peculiarity is worthy of the attention of pathologists and 
of naturalists; for if man does not spontaneously breed any of these 
diseases, he has nothing to do but to keep out of the way of these 
morbific influences. Fatigue, bad food, the accumulation of a 
great number of individuals, sound or sick, in a small space—all 
the conditions analagous to those to which veterinary surgeons 
generally attribute the spontaneous development of glanders, have 
never produced it in the human being. 
In man, and in the human being, there appear to be certain con¬ 
ditions inherent in his organization which prevent the spontaneous 
development of glanders. It is so in the ruminants and the car¬ 
nivora. 
