385 
ON GI.ANDEliS IN MAN, &c. 
may be the seat of the eruption, but more rarely. Also when 
glanders is transmitted from the horse to the dog by means of 
inoculation, the scrotum is sometimes attacked by inflammation 
and gangrene, while other parts are spared. In general, however, 
acute glanders being considered as easily communicable to other 
animals, we hasten to destroy those that are infected, and before 
the disease can have passed through all its stages. At all times, 
however, it is the fact, that the glanderous eruption is less frequent 
on the skin of the horse than of that of the human being. 
The different structure of the skin in man and in the horse 
seem to explain to a certain degree the difference which is observ¬ 
able in the frequency and extent of the glanderous cutaneous erup¬ 
tion. It even appears, on studying comparatively the febrile and 
eruptive maladies of man and the mammiferous animals, that the 
collection of the roots of the hair on the tissue of the skin is an 
obstacle to the development of these eruptions. Thus, not only 
the glanderous eruption of the horse shews itself especially on his 
muzzle and scrotum, but it is equally on the parts deprived of or 
little provided with hair—on the lips, the udder, and in the inter- 
inguinal space—that the aphthous inflammation of cattle is princi¬ 
pally found. Also the vaccine disease, analogous to the variola 
of the human being, is seen on the udder and around the mouth. 
The eruption also of the claveau and charbon among sheep, shews 
itself principally in parts deprived of wool. 
In the horse attacked by acute farcy-glanders, the cellular tis¬ 
sue, and the lymphatic vessels which permeate it, become inflamed, 
and suppurate as in the human being. In the horse, as in man, 
attacked by farcy-glanders, filtrations of pus and depots of plastic 
lymph have been found in the interstices of the muscular fasciae; 
but the cellular tissue of the horse presents more rarely than that 
of man the multiplied, voluminous and extensive abscesses which 
we have observed in the farcy-glanders of the human being. This 
is to be accounted for by the less aptitude in the cellular tissue of 
the horse—an unecpial aptitude, and much more remarkable in 
other species of animals, in which it is difficult to produce any sup¬ 
puration, as in birds. 
In man, as in the horse, we have often observed in farcy-glan¬ 
ders little depots of pus between the periosteum and the bones 
of the skull. We have, also, seen these bones attacked by caries. 
These cases, however, are of rare occurrence, and have been 
denied by some surgeons. As to the relative frequency of these 
changes in the bone in man and the solipede, it is not possible to 
speak with certainty, on account of tlie want of sufficient compa¬ 
rative researches; yet tlic study of them is a matter of very consi- 
