386 
ox GLANDKliS IN MAN, &c. 
derable importance. It is, in truth, far more interesting than tliey 
who have not thought seriously of the case imagine. It it an un¬ 
deniable fact, that many medical men, not knowing that similar 
lesions have been observed in glanders, have not scrupled to attri¬ 
bute certain changes of the bone to the caries of the venereal dis¬ 
ease, when there has not existed a single other concomitant of 
syphilis, and when the proof of venereal affection could never be 
furnished. The simple fact, that certain lesions of the bone, re¬ 
cognized as glanderous in the horse, have been attributed to 
syphilis by some human surgeons, should be deemed sufficient to 
establish the propriety of a parallel and comparative study of the 
diseases of men and animals. 
There have been observed in man, as in the solipede, during 
glanders coupled with farcy, an inflammation of the veins, and of 
the lymphatic vessels and glands, nearly in the same proportion. 
The lesions of the digestive apparatus are very slight both in 
the human being and in the horse, if we except those of the liver, 
and particularly of the spleen, in which spots of induration and 
depots of purulent matter are frequently found. 
These abscesses or depots are occasionally found in the kidneys, 
both of the human being and the horse. 
In fine, all the lesions observed in acute and chronic glanders 
in the horse have attended the same diseases in the human being. 
The differences which we have indicated are, in the human being, 
less nasal discharge—sometimes the appearance of the natural se¬ 
cretion—greater frequency of pustular and gangrenous eruption of 
the skin—a slight enlargement, or none at all of the submaxillary 
glands, and a difference of morbid structure in the parts affected 
to a greater or less degree. 
The diagnosis of acute glanders does not present more difficulty 
or incertitude in the human being than in the solipede. At a 
former period, when the existence of this malady was not suspected 
by medical men, and when they were not in the habit of examin¬ 
ing the nasal fossae after death, acute glanders was often con¬ 
founded with malignant pustule, or, rather, they designated it under 
the name a charhonous affection with an anomalous eruption: but 
acute glanders differs from the malignant pustule in a crowd of 
particulars. In glanders, the constitutional symptoms precede the 
eruption of the skin: in the malignant pustule the charhonous 
affection is primitive. In the latter, we observed neither the 
multiplied farcy abscesses nor the glanderous and characteristic 
eruption in the nostrils. Acute glanders in the human being is, 
« perhaps, of all eruptive fevers, that of which the diagnosis is most 
easy; and that is now so certain, that there has not been an error 
