ox GLAXDEMS IN MAX, S:c. 387 
of diagnosis with regard to one of the fifteen patients that have so 
rapidly succeeded to each other. 
In man, the abscesses multiply, and a pustular and gangrenous 
eruption of the skin are sometimes the first positive signs of a 
glanderous infection; and they are well characterized before the 
eruption of the nasal fossae and the discharge from the nose can be 
affirmed. In the horse, on the contrary, the certainty of the diag¬ 
nosis depends, most of all, on the existence of the nasal discharge, 
and of the pustular and gangrenous eruption in the nasal fossae—an 
eruption easy to be perceived on the nasal septum, and slightly 
on enlarging the opening of the nostrils. 
The diagnosis of chronic glanders is much more easy in the 
horse than in man. In fact, separate from the small number of 
cases in which a foreign body has been introduced accidentally 
into the nasal fossae, or a cancerous degeneracy of the same parts, 
causes an habitual discharge from the nostrils, every case of chronic 
nasal discharge, with enlargement of the glands, belongs to chronic 
glanders. In such cases, the veterinary surgeon has not, like the 
practitioner of human medicine, to inquire whether the ulcerations 
are mot rather syphilitic, or scrofulous, than glanderous. 
The veterinary surgeons and the medical men are, to the present 
day, completely at a loss as to the treatment of glanders. As to 
the solipede, glanders in its acute and its chronic state is incurable 
in an immense majority of cases; and, in man, it is always fatal. 
That which is of most importance in the present state of science is 
to prevent the development of glanders in the solipede, by removing 
every agent that can possibly contribute to its growth, or which 
can favour its transmission either by infection or contagion. 
That which is of principal importance is, no longer to propagate any 
doubt as to the contagious property of the disease—a contagion 
which is too frequently proved by the ravages which glanders ordi¬ 
narily makes among horses of the same establishment, when one 
or more already glandered are introduced there; and, also, by the 
ravages of this complaint in the barracks of the French army, wdiere 
the sanitary regulations are carelessly applied; and, still more 
plainly, by the transmission of glanders from the horse to the human 
being—which is confirmed, if it wanted confirmation—by the con¬ 
fessions of the individuals who have been attacked by this frightful 
disease; and still more confirmed—if confirmation were wanted— 
by the development of glanders in the horse and the ass when they 
are inoculated with the virus of glanders, whether it proceeds from 
the horse or from the human being. A contagion, in fine, which 
has been proved by so many facts, and by so many experiments 
and testimonies, that the moment is come, and the opportunity now 
