IN Do:\rESTrc animals. 
533 
the disease which we liave been just describing. The same causes 
produce it, and the same symptoms designate it, but with some¬ 
what less intensity. The early symptoms are promptly followed 
by the appearance of sanguino-serous tumours on the breast, or 
between the thighs. These tumours are rarely perfectly circum¬ 
scribed, and always tender and painful towards their centre. If they 
are cut into it will be found that they are formed at the edge of 
some serous effusion, of a yellow colour, and having in its centre 
a deep-coloured central point of black blood. 
The appearance of these tumours is generally accompanied by 
an improvement in the state of the animal. “It would seem,” says 
M. Delafond, “ that nature has eliminated an altered kind of blood 
while depositing it in the sub-cutaneous cellular tissue. This appa¬ 
rent improvement, however, is but of short duration. If the surgeon 
does not hasten to adopt a rational and decisive mode of treatment, 
the scene presently changes—the tumour extends in every direc¬ 
tion, and Irecomes particularly softened at its centre—a foetid hu¬ 
mour exudes from the skin—gangrene develops itself, and death 
speedily follows. 
On examination after death, we find all the disorganization that 
has been described, and, in the tumours, three remarkable lesions. 
At the exterior there is a yellow serosit}^; at the centre there is a 
broken-down putrid mass, resulting from gangrene of the solid 
parts, and decomposition of the blood; and, finally, on the tissues 
that are not sphacelated, black spots are formed by the deposition of 
hematosine. 
In order to arrest the progress of the disease, and the appearance 
of the gangrene, M. Delafond recommends to make incisions into 
the tumours, to press out the blood and serosity which they con¬ 
tain, and to cauterize them deeply. He advises also the adminis¬ 
tration of tonics and of antiseptics, means which, in other cases, 
have not been sufficiently estimated. 
The rapid progress of the maladies that are connected with 
PeloJtemia —the lesions which they determine—tli^ peculiar state 
of the blood, and, more particularly, iis virulence —all demonstrate, 
according to M. Delafond, an essential change in the constituent 
materials which constitute that fluid. 
M. Delafond terminates his labours by instituting a comparative 
examination of the diseases attributed to a change in the blood in 
man and in the inferior animals. lie finds a great analogy be¬ 
tween the plethora of the human being and the pelohemia of the 
(luadrupecl. The anhemia and hydrohemia seem also to present 
the same characters in man as in the quadruped; and “La rnaladie 
tachetee of Werlhoff” — a disease in the human being consisting of 
a multitude of rounded spots, red or brown, spread over the whole 
VOL. XIII. 4 B 
