G86 
COMP'FK UFA’DU OF 
of the hospital, and 4000 have undergone examination. Besides 
these advantages, the pupils of the fourth year have, under the di¬ 
rection of the professors, undertaken the medical care of a great 
many horses and other animals belonging to persons living in the 
immediate neighbourhood of the school. 
Acute Glanders. —MM. Renault and Bouley have continued 
their researches on this disease. An inquiry into the nature of this 
malady, its symptoms, and, more especially, its contagious property, 
has acquired increasing interest since its transmissibility from the 
horse to the human being has been lately proved in so many in¬ 
stances. MM. Renault and Bouley have arrived at the following 
results. 
Contagion. —1. Acute glanders is contagious by inoculation 
from horse to horse. Every experiment of the last and the present 
year has given this positive constant result. Without a single 
exception, the symptoms of the infection of glanders have appeared 
in the inoculated animals from the third to the fifth dav, and death 
has ensued between the tenth and fifteenth days. 
2. Acute mange is communicable from horse to horse by coha¬ 
bitation. Many experiments during the last year have rendered 
this incontestible. Nevertheless, with regard to the second point, 
it should be observed, that the contagious properties of acute glan¬ 
ders are rendered more manifest by inoculation than by cohabita¬ 
tion. Very few horses resisted the inoculation; while more than 
half of those subjected to cohabitation with glandered animals re¬ 
mained safe and sound, although they had been with infected 
horses from the commencement to the fatal termination of the dis¬ 
ease. 
3. Acute glanders,—is it transmissible from the horse to other 
animals ] This third point is of the utmost importance with refer¬ 
ence to the etiology of glanders in the human being. MM. Renault 
and Bouley have already given an account of their having inocu¬ 
lated the sheep, the dog, and the pig with the matter of glanders. 
The first results of these experiments seemed adverse to the trans¬ 
missibility of glanders from the horse to animals of a different spe¬ 
cies. In fact, when the last compte-rendu was published, the two 
sheep seemed to have resisted the power of the virus, for they pre¬ 
sented every appearance of health; but they died in a state of 
excessive marasmus, and with all the symptoms of acute glanders, 
five or six months after the inoculation. Examination shewed the 
same lesions in the cavities of the nose that are found in those of 
the horse. 
A series of experiments directed to the same object with regard 
to the dog, the sheep, and the swine, has been undertaken by MM. 
Renault and Bouley, and which they purpose shortly to publish. 
