PAUL pry’s reminiscences. 
115 
affection in the nostrils is secondary. When the lungs are sim¬ 
ply hepatized, a cure may be effected. Another stage of the 
disease is the tuberculous ; in this stage, likewise, a cure may be 
effected : but when the tubercles begin to suppurate, they run 
into one another, forming large abscesses, which discharge their 
contents through the bronchiae : at this stage of the disease the 
animal had better be killed. I have ascertained, by repeated 
experiments, that the matter of a tuberculous lung w'ill produce 
the disease in another horse, by inoculation, as surely as one 
potatoe will produce another. 
** With respect to the manner in which the tubercles are formed, 
that exist in the great majority of cases of glanders, this is as 
yet far from being determined. Some veterinarians are of opinion 
that they are distinct morbid tissues; others regard them as the 
production of a morbid secretion. I confess that I am inclined 
to agree in the latter opinion, that a tubercle is the product of a 
morbid secretion, and that this process is preceded by an active 
congestion in the part, similar to that which occurs in every case, 
while secretion is going on, whether healthy or unhealthy. 
With regard to my treatment of glanders, you must all be very 
well acquainted ; it consists in the administration of the sulphate 
of copper in a solution of water. This mineral may be given to 
the extent of two ounces for one dose in this manner; but if 
given in a solid form, it would occasion inflammation of the coats 
of the stomach. By being dissolved in water, this is prevented, 
and it acts in a more general manner. 1 have usually given from 
four drachms to one ounce daily : it should be given on an empty 
stomach, as it is apt to be decomposed by any acid that may be 
generated there. I know that even three ounces of the sulphate 
of copper, dissolved in a quart of water, may be given every 
other day, or every day, if so large a quantity should be re¬ 
quired. Mr. Percivall informed me, that he has given three ounces 
in a ball to a horse for one dose ; but this, m my opinion, is 
dangerous practice. I have already cured two glandercd cases 
this year ; and I have great hopes, especially as the season of 
the year is rather unfavourable to the thing, of effecting another 
cure; for, if they can be cured at this season, they may be cured 
at any time. As a local remedy I have applied setons with good 
effect. It was a common practice formerly to apply rowels un¬ 
derneath the jaw, but this is, in my opinion, too far from the seat 
of the inflammation. With regard to diet in this disease, the 
animal should have his constitution kept up by nutritious diet: 
fine flour is a very excellent diet in this complaint, as it contains 
a great deal of nourishment in a small bulk.'’ 
This was the principal part of a discourse delivered by Mr. 
