CONGENITAL, HEREDITARY, CHRONIC GLANDERS. 197 
cerations on the nasal membrane on the same side. The animal 
was suckled by the mother, and appeared to be in perfect health, 
with the excepUon of the circumstances already stated. 
Little change took place during the first two months of the 
animal’s existence. In the third and iburth months the respira¬ 
tion through the right nasal cavity was accompanied by a nasal 
sound, and exercise considerably augmented it. The appetite 
and spirits were unaffected. 
The mare was destroyed in the month of October, and I had 
opportunity to examine the colt in the subsequent December. 
The lymphatic ganglions of the mesentery contained tubercles 
of different sizes. The mesentery itself, in various parts, parti¬ 
cipated in the same disorganization. Five or six pounds of a 
yellow serous effusion were found in the abdominal cavity. There 
was little injection in any part, but every thing betokened a sub¬ 
acute inflammatory state. 
The bronchial glands were indurated, but not in so great a 
degree as the glands in the thoracic viscera. The other thoracic 
viscera were sound. 
The left nasal cavity presented nothing unusual; but there 
were deep ulcerations in the frontal and maxillary sinuses on the 
right side, and the turbinated bones were nearly destroyed: the 
bony parietes of their cells were softened, and denuded of their 
mucous membrane, and which was, here and there, replaced by 
vegetations resembling transparent jelly, of a light green hue. 
There were eight of these morbid productions, varying in size 
from a horse-bean to a laroe nut. 
At the superior extremity of the nasal cavity was a polypous 
production, three or four inches#in length; it looked like a 
middle-sized pear. Its parietes were thick, yet soft; and, on being 
cut into, a small quantity of white fluid ran from it. 
The whole nasal cavity contained almost innumerable small ulcer¬ 
ations, for the most part not extending beyond the mucous tissue. 
This case (and others resembling it frequently occur) does not 
])rove that glanders is contagious; but the conclusion is inevi¬ 
table, that it is hereditary. I believe that the disease may be 
traced to vitiated nutrition ; for the foetus, forming an integrant 
part of the mother, owes its development to nutriment imperfectly 
absorbed, because the principal viscera of the mother are a prey to 
disorganization very considerably advanced. 
There is no doubt that the mesenteric and bronchial indura¬ 
tions observed in the animal derived their origin from this cause, 
and th(‘ir morbid condition spreads sympathetically towards the 
pituitary membrane; for when this irritation is once developed, 
it is capable of propagating itself indefinitely, attacking suc- 
VOL. VI II. E e 
