TOXICOLOGY. 
519 
CASE I. 
Oct. 25, 1834.—1 administered to an aged horse, of moderate 
size, two ounces of arseniate of potash, and immediately after¬ 
wards one pound and a half of the hydrate of the peroxide of 
iron, dissolved in two gallons of water. The animal, that had 
been cast the better to enable us to administer the bane and the 
antidote, got up without difficulty. During about two hours he 
seemed to be much depressed, and then he regained his gaiety and 
usual appetite. This continued until the following day at noon, 
when he seemed to be exceedingly dull, and refused all kind of 
food. In the early part of the night he had slight colicky pains 
and frequent diarrhoea; these rapidly increased, and he died 
about four o’clock on the morning of the 27th. 
Post-mortem examination^ sixteen hours after death.—Inflam¬ 
mation of the peritoneum, and injection of the vessels of the 
epiploon. The lining membrane of the right sac of the stomach 
was red, thickened, and ecchymosed through its whole extent; 
and at some points abraded. The small intestines presented the 
same appearances, but less marked; the caecum and colon were 
filled with the antidote, and their lining membrane was intensely 
red, and double its natural thickness. In short, this horse pre¬ 
sented precisely the same lesions that were found in the seven 
that were poisoned by the arseniate of potash, and it was evident 
that the antidote had failed, although administered immediately 
after the poison. 
I should have repeated the experiment had I not heard that 
Messieurs Renault and Lassaique had tried the effect of this 
antidote on several cases with no better success than I had expe¬ 
rienced. M. Lassaique then kindly suggested to me that, al¬ 
though he knew that the hydrate of the peroxide of iron was an 
antidote against arsenious acid, it might fail against the arseniate 
of potash, on account of the greater affinity which the arsenious 
acid had for the potash ; I therefore determined, instead of the 
antidote of Bunzen, to try the sulphate of iron, under the hope 
that the laws of chemistry would be obeyed, and that the bane 
and the antidote would be decomposed, and sulphate of potash 
and arseniate of iron be produced; the former harmless, and 
the latter not sufficiently powerful to destroy life. I proceed to 
relate the result. 
CASE II. 
A"ou. 1834.—Two ounces of the arseniate of potash were 
given to an old grey horse, of middle size, at nine o’clock in the 
morning, and, immediately afterwards, a pound of sulphate of 
