SYMPTOMS OF GLANDERS. 
133 
The appearances of the lungs to which I would chiefly direct 
your attention, and as throwing great light on the primary seat 
of the disease, are these—viz. the occasional absence of any 
morbid affection of the lungs, even in the most aggravated cases 
of glanders, and the correspondence between the lung that may 
be affected, and the nostril whence the discharge proceeded. 
A record of nineteen cases of discharge from the left nostril 
presents the following results:—In four, no affection of the 
lungs; in ten, congestion or hepatization, or other marks of in¬ 
flammatory action in the left lung only—the right lung was per¬ 
fectly sound : in two cases, both lungs were affected, but the 
left lung most so; and in three cases both were nearly equally 
affected. In eight cases of discharge from the right nostril, two 
presented no disease of the lungs; in four, the right lobe only 
was diseased; in one, both were affected, but the right lung 
most violently ; and in one, both lungs were equally diseased. 
In ten aggravated cases there was discharge from both nostrils; 
the left lung only was diseased in one; and in the other nine, 
both presented nearly equal traces of inflammation. The lesions 
of the abdominal viscera, and of the brain and its membranes, 
seemed to be perfectly accidental. 
We are now, I think, gentlemen, prepared to come to some 
satisfactory conclusion as to the primary seat and nature of glan¬ 
ders in our next lecture. 
LECTURE VIII. 
GLANDERS CONTINUED. 
The Lining Membrane of the Nose the primary Seat of Glan¬ 
ders .—There can be no doubt I think, gentlemen, of the con¬ 
clusion to which we must arrive, that the primary seat of glanders 
is the lining membrane of the nose. A discharge from the nostril 
is that which causes the disease to be first suspected, which 
attends it through every period of its course, and accompanies it 
at its fatal termination. It is inflammation of the pituitary 
membrane, recognized by that which is the earliest and invariable 
symptom of inflammation of a mucous surface, increased secre¬ 
tion—secretion altered in character as well as quantity, becoming 
vitiated, acrimonious, malignant. I will not enter into the con¬ 
troversy whether it is a specific inflammation—one that is not 
governed by common laws—or whether the malignant and infec¬ 
tious character which it speedily assumes may be traced to the 
extreme vascularity and sensibility of the membrane, and the 
absurd and injurious irritation to which it is so much exposed. 
