210 MR. youatt’s veterinary lectures. 
one drop of our injection into the upper part of the nostrils. Be¬ 
side this, if we could get it there, we should but add fuel to fire ; 
for glanders was caused by this membrane being exposed to un¬ 
natural irritation, and morbid irritation of any and of every kind 
has a necessary tendency to produce glanders; therefore, gen¬ 
tlemen, no injection, if you please, and, least of all, those acri¬ 
monious ones which can only torture the animal and hasten the 
termination of the affair. 
Counter-Irritants .—Blisters, or setons, along the nasal bones, 
or the sutures between them and the superior maxillaries, or 
over the frontal sinuses, if the horse should give indication of 
pain when pressed there, are far more surgical-like measures, 
and should rarely be omitted in our treatment of glanders. There 
we are properly resorting to the use of counter-irritants; but per¬ 
chance the seat of this local inflammation may not be within the 
reach of these stimuli, however powerful. 
Tonics, particularly the Sulphate of Copper .—Glanders is a 
chronic inflammation of the membrane of the nose, debilitating it, 
and at length producing general debility. Tonics would appear to 
be indicated, in order to sustain the system against the insidious 
effects of this long-continued irritation; or to excite another, and 
healthier, and more powerful action, and before which the other 
must succumb: but, then, can we find a tonic which, while it has 
effect on the constitution generally, exerts its chief power on some 
particular part, and that part the Schneiderian membrane? Most 
of our medicaments have this local as well as general effect. I 
believe that we have this general tonic, with a peculiar local deter¬ 
mination, in the sulphate of copper. Its effect in healing nasal 
abrasions and arresting nasal gleet is undeniable. How should 
it be administered? Not in doses which alter its character, 
and depress instead of supporting, destroy instead of rousing, 
the principle of vitality. You must not, by your incautious and 
rude assistance, knock the staggering man fairly down. Sul¬ 
phate of copper in small doses, gradually increased from half 
a drachm to two drachms daily, or twice in the day, combined 
with some vegetable tonic that does not decompose it, and 
especially combined with an aromatic and stomachic, is worth 
trying. And then if this drug should ever be established as 
possessing power in the cure of glanders, let the meed of praise 
be yielded to Mr. Sewell, who first directed our attention to 
it; but against the enormous doses in which it used to be, 
and I believe still is, administered by that gentleman, I must 
record my decided protest. I have never seen permanent good 
from them; but many a horse has rapidly sunk under the ex¬ 
cess of stimulus. 
