152 
GLANDERS IN THE HUMAN BEING. 
The most important lesion, however, was found at the base of 
the larynx, where was a veritable glanderous chancre, with perfect 
elevated, abrupt, and everted edges; but its central depression 
was not so great as is usually seen in the horse. Near this w'as 
also a preparatory vesicle. 
The lining membrane of the trachea was slightly inflamed, the 
bronchi more so, and puriform fluid might be squeezed out of 
many of the bronchial ramifications; but there was neither vomica 
nor tubercle. The other viscera were comparatively healthy, 
except that in the lower portion of the colon there were many 
enlarged glands, and even the membrane seemed abraded, an 
appearance which accounted for the diarrhoea. 
On the whole, the examination was satisfactory—the charac¬ 
teristics of glanders were sufficiently developed, but modified by 
the difference of the subject. 
The possibility of the communication of glanders from the 
quadruped to the human being has long been suspected, or rather 
painfully known by the veterinarian ; but to Mr. Brown, the 
Surgeon of the 2d Regiment of Dragoons, we are indebted for 
the first recognition of the disease among medical men. He 
published in the Medical Gazette for July 4, 1829, the his¬ 
tory of a case which had occurred in his regiment, and en¬ 
titled it ‘‘ Fatal Case of Acute Glanders in the Human Subject,’^ 
A case had been admitted into St. Thomas’s Hospital, under 
Dr. Roots, in March, and another under Dr. Elliotson, in June, 
in the same year. These gentlemen were satisfied that their 
patients fell victims to some morbid poison, and ‘‘ a poison 
furnished by a living system under the same disease;” but the 
nature and source of this poison they could not discover; they 
could not even guess at them: for they were unable to elicit 
from their patients any thing satisfactorily to guide them. When, 
however, Mr. Brown’s case appeared in July, Dr. Elliotson (in^an 
interesting account of these cases, and also a valuable epitome 
of all that has been reported by British and foreign authors, 
published by him in the 16th volume of the Medico Chirurgical 
Ti'amactions), very honourably acknowledges, It instantly 
flashed upon my mind, that this must be what I sought.” We shall 
take an early occasion of referring to Dr. Elliotson’s paper, and 
