THE TKYPANBLUE TREATMENT IN PIRO- 
PLASMOSIS OF DOMESTICATED ANIMALS 
IN SOUTH AFRICA. 
By a. GOODALL, M.R.C.V.S. 
Government Veterinary Surgeon, Union of South Africa. 
The following brief notes on the above subject are the outcome of 
the writer’s experience in the use of Trypanblue in cases of piroplasmosis 
in animals. The inoculations were undertaken under strictly practical 
conditions in up country districts, and whilst no new discoveries are 
claimed, it was thought that this short description of the purely utilitarian 
employment of the drug might prove of interest. 
Strength of Solution. The writer has used throughout a 2®/(| filtered 
and sterilized solution of the drug made with rain-water. 
Dosage. 
Dog: 5—30 c.c. (hypodermically) according to height and age. 
Horses and Large Alides: 200 c.c. 
Donkeys, Ponies and Small Mules: 150 c.c. -intravenously. 
Cattle: 50-250 c.c. (according to age and size); 
Diagnosis. Wherever possible blood smears were examined micro¬ 
scopically, but in many cases owing to the exigencies of field conditions 
diagnosis had to be made by clinical symptoms alone. 
Biliary Fever of the Dog (Piroplasma canis.) 
The writer has had excellent results with the drug in this disease, 
and would almost feel tempted to describe some of the recoveries as 
“ miraculous.” 
The injection has always been made hypodermically on the chest 
wall, as great difficulty is often experienced in introducing a needle 
into the vein of the dog’s thigh, especially when the animal is in the 
