A. Goodall 
anaemic state so often encountered in this disease. If an abscess forms 
at the site of injection—a not uncommon occurrence owing to tlie 
irritating nature of the drug, even when the most rigid aseptic precau¬ 
tions are observed—it never causes serious inconvenience if opened and 
treated in a suitable manner. 
A Few Cases. 
Case I. Subject. Crossbred Irish terrier, weight about 40 lbs. 
When seen by the writer was in a very advanced state of the disease. 
Temperature 104'2°-105° F., pallid mucous membranes, and passing 
urine the colour of dark ale. Smears from the peripheral blood showed 
a heavy infection of the parasite and marked anaemic lesions. It was 
not possible to obtain the drug until the following day when the animal 
was in a state of collapse and literally unable to lift its head. 20 c.c. 
of the 2 Yo solution were injected subcutaneously on the chest wall, more, 
it must be admitted, in the nature of an experiment than anything 
else. Twenty-four hours after the injection the animal was well 
“blued” all over, and the writer was astonished to see it barking and 
looking for food. An uninterrupted recovery was made without abscess 
formation. 
Case II. Subject. Wire-haired terrier, weight about 25 lbs. 
A typical clinical case well advanced, and smears showed a heavy 
infection. 15 c.c. of a 2Yo solution were injected on the chest wall. 
Twenty-four hours afterwards the animal was well “ blued ” and smears 
showed a great decrease in the number of the parasites. The subject 
made a good recovery and was an interesting case, inasmuch as the 
writer was able to take smears at twenty-four hour intervals for a week 
after injection to watch the disappearance of the parasites from the 
blood. None were seen after the fourth day and those which were 
encountered after the first twenty-four hours looked shrivelled and 
“ sick.” It was also noticed that the anaemic lesions in the blood 
quickly disappeared, until in a week’s time it could have been described 
as “ normal.” 
Case III. Subject. Bulldog, weight about 30 lbs. 
Was noticed “off colour” for .some days and gradually got worse; 
no marked clinical symptoms were observed for four days although the 
temperature gradually rose from 102° to 105° F., blood smears examined 
