66 
Treatment in Piroplasmosis 
appeared to be in an almost collapsed condition—there was no oppor¬ 
tunity to examine blood slides. 200 c.c. of a 2“/o solution of Trypanblue 
were injected into the jugular vein and next day a marked improvement 
had set in. The animal was eating a little and the temperature had 
subsided to 102'4° F., the mucous membranes were slaty-blue (they 
never take on such a bright blue colour in equines as they do in the 
dog after an injection of the drug); recovery was slow but complete. 
The above typical cases in the horse and mule, out of some scores 
treated by the writer, will serve to demonstrate the quick and safe 
action of the drug. In his hands it has proved a most practical and 
efficacious treatment for this disease. But he trusts that it will not be 
« 
brought into disrepute by being employed by unskilled persons as a 
panacea against every malady to which equine flesh is heir. 
The writer has not encountered relapses after recovery although 
this is, of course, slower in some animals than in others, depending, in 
the writer’s opinion, on the duration of the infection before treatment, 
the extent of the anaemic lesions present in the blood, and the par¬ 
ticular susceptibility of certain animals. He has also never seen 
pneumonia supervening after the animal has been injected with 
Trypanblue, but this was a fairly common sequel with the calomel- 
chloride of ammonium treatment when the animal had apparently quite 
recovered from the piroplasmosis. 
Firo 2 )lasmosis of Donkeys (Piroplasma caballi ?). 
On account of the restrictions placed on ox transport owing to East 
Coast Fever in 1910, a large number of donkeys were introduced into 
the Mount Currie district of East Griqualand from all over South 
Africa—-chiefly from non-biliary fever areas. As has already been 
stated. East Griqualand is a notoriously bad district for biliary fever 
in horses and mules, but these highly susceptible donkeys failed to 
contract piroplasmosis until they commenced going into Pondoland 
some eighteen months afterwards, when they soon developed a disease 
which the writer took to be “ biliary fever.” The explanation of the 
animals failing to contract the disease in East Griqualand, howevei', 
remained unsolved until his attention was drawn to a paper by 
Nuttall and Strickland (1912) in which the authors made a distinction 
between Nuttallia equi (Laveran) and Piroplasma caballi Nuttall, and 
he is now strongly of the opinion that these donkeys were susceptible 
