J. F. Valladares 
89 
The cases recorded below were all in-patients at the Madras 
Veterinary Infirmary. There were several cases of which no mention 
is made in this paper, but in which the disease was verified by micro¬ 
scopical examination, the infection being due to either P. cahalli or 
N. eqid. 
Case 1 (Nuttalliosis). Since the two species of parasites above 
referred to were differentiated and classified, probably the first observa¬ 
tion in India, here recorded, was made on a Gelding, the property of 
Mr G. F. Paddison, I.C.S. The horse was admitted into the Madras 
Veterinary College Hospital as an in-patient foi- treatment for biliary 
fever on 19th September 1912. It appears the horse had been taken 
to various parts of the Presidency, so that it was difficult to determine 
the precise place at which the animal became infected. It was 
ascertained that the animal was frequently inclined to be sluggish 
in its movements for short periods of time but this condition evidently 
had no bearing on the disease. 
The symjjtoms observed at the Infirmai’y were briefly as follows:— 
the conjunctival mucous membranes, at first of a pale yellow colour, 
became subsequently hyperaeraic with serosanguinolent infiltration. 
At a later stage well marked petechiae were noticed on the membrana 
nictitans. The appetite was irregular, the animal now and again 
eating a little corn and grass. Dulness was noticed from the beginning; 
the animal presented appearances of weakness and had an unsteady 
gait almost terminating in paraplegia before death. Haemoglobinuria 
was observed on the last .seven days. Fever was present, a maximum 
of 107° F. was recorded on 30th September in the evening ; it fluctuated 
slightly to the time of death, at 6 p.m. on 7th October 1912. 
The parasites in the periphei’ial blood were first noticed on the 
morning of 30th September. They were found in large numbers and 
included the spherical, piriform and rosette varieties. All these forms 
could be distinguished fairly easily from the start and they increased in 
number as death approached. 
The Autopsy revealed several morbid changes; well marked general 
bile staining of the subcutaneous tissue; liver considerably enlarged, 
jaundiced, weight 20 lbs.; spleen enlarged, weight 9 lbs.; kidneys much 
enlarged, congested and icteric, each kidney 2 lbs.; heart enlarged, 
contained hardly any blood. 
Subinoculation Experiment. Previous to death two horses were 
inoculated (2. X. 1912) from the blood of horse 1, 18 c.c. into an aged C. B. 
Gelding, and 20 c.c. into an aged Waler Mare, both intravenously. The 
result was negative. 
