ON RABIES. 
621 
AVhat has been tlie result ?—It has not produced it. 
Then is it your opinion that the virus communicated by inoculation from 
any animal will not produce the disease in another ?—I have not been able to 
do it, and, judg’ing from my own experiments, I do not believe it does. 
Then do you believe that it is the bite alone, and the laceration attending 
it, which produces the disease ?—Yes, the experiments lead me to that con¬ 
clusion. 
Have you had many instances of horses dying in your hospital ?—Yes, and 
out of it, out-patients; one not more than three weeks ago, JMr. Cubitt, the 
builder, of Belgrave Square, lost a very fine horse from the bite of a dog. 
Are the symptoms attending the disease of hydrophobia in horses the 
same as in man ?—Yes; it is more distressing than any other disease in the 
horse, even tetanus or lock-jaw, and phrenitis or brain fever. 
You mean that the convulsions in the patient are greater than you have 
seen in any other disease?—Yes, much more distressing or agonizing. 
Do they invariably die in convulsions ?—Generally ; but they have occa¬ 
sionally paroxysms so severe, that they become exhausted, and die tran¬ 
quilly; there are periods of suspension from those violent symptoms, in 
which they may be managed, but during the paroxysms they bite and kick, 
and are quite unmanageable. 
Is it your opinion that during these paroxysms they are quite insensible 
of what they are about ?—^Yes: it is an uncontrollable ferocity ; differing from 
that produced in persons by drunkenness or disease, by a sudden return to 
calmness and obedience. 
Have you seen any cases of severe tetanus?—Yes, many. 
Are the symptoms attending hydrophobia nearly similar, or of the same 
kind that attend tetanus?—Very like; but you have a remission of the 
paroxysms, which is continual in tetanus. 
Have you ever observed the same rigidity of the human frame in hydro¬ 
phobia as in tetanus?—I have seen persons convulsed in hydrophobia in the 
same manner as the horse is. 
What is your observation as to the frequency of the disease now, com¬ 
pared with former periods?—I have heard of more within the last two years ; 
for some years I never heard of a case, up to twenty years past. 
In cattle you mean ?—In horses, sheep, and cattle in and about London. 
Can you account in any way for the more frequent occurrence of that 
disease now than formerly?—I think that this arises about London from the 
employment of dogs in carts; they are over-exerted, which brings on fevers, 
and whenever they have any attacks of fever, they are exposed to rabies from 
fatigue, and the pain and irritation of the feet, and abrasions and galls from 
the harness. 
You have frequent communications, I presume, with those who have been 
your pupils at the College, who are now in diflferent parts of the country ; 
have you ever inquired of them how far the disease is more frequent in dis¬ 
tant parts of the kingdom than formerly?—I have not. I have wished to 
have sheep and cattle that have been bitten conveyed to town, in order to 
watch the progress of the disease, and endeavour to find out a remedy; if 
the Committee will allow me, I will shew them some drawings of the appear¬ 
ance of the brain and spinal marrow in the human species, and also in horses 
after death from this disease. 
[The witness exhibited the drawings alluded to!] 
You have now exhibited drawings shewing a high state of inflammation in 
the spinal marrow of horses and in the human species, where death has been 
the result of hydrophobia; is it your opinion that any irritation and heat which 
VOL. XI. 4 N 
