Gr. H. F. Nuttall 
59 
numbers in the calf’s blood. The drug exerted no effect whatever. 
(See protocol, p. 71.) 
XII-XIII. Quinine hihydrochloride. In Exp. XII the animal 
received on 14 successive days subcutaneous injections of 55 to 60 grains 
dissolved in 25 c.c. of water. Treatment commenced on the third day 
of the appearance of parasites in the animal’s blood. In Exp. XIII 
quinine hydrochloride was given on five successive days followed by 
the bihydrochloride on seven out of nine days, the drug being injected 
intramuscularly. Treatment in this case began on the first appearance 
of parasites in the calf’s blood. No effect was observable from the 
treatment. (See protocols, pp. 72-74.) 
XIV. EtJiylhydrocupreine HCl, 24 c.c. of an 8 % solution was 
injected subcutaneously on five successive days, beginning on the second 
day after the appearance of parasites in the calf’s blood. The result 
was negative. (See protocol, p. 75.) This drug had been recommended 
because of its bactericidal effect in pneumococcus infections. 
XV. A7nmonium fluoride, 0-5 % in 0‘8 % NaCl solution was injected 
in doses of 18 to 20 c.c. intravenously on nine successive days. Treatment 
began on the second day of the parasites appearing in the calf’s blood. 
There was no observable effect. (See protocol, p. 76.) The trial of 
ammonium fluoride was suggested by its known inhibitive effect on 
bacteria producing lactic and butyric acid fermentation without inter¬ 
fering with the growth of yeast. 
XVI. Potassium iodide in 25 % solution was injected intravenously 
on five successive days, the dose ranging from 20 to 40 c.c. Treatment 
commenced a day before the parasites appeared in the animal’s blood 
but the result was negative. (See protocol, p. 77.) 
XVII. Calcium lactate in 10 % solution was injected intravenously 
on seven successive days, the dose ranging from 3 to 5 c.c. Treatment 
began on the second day of the appearance of parasites in the calf’s 
blood. There was no effect observable. (See protocol, p. 78.) 
XVIII. Nuclein from thymus gland, 10 c.c. of a 5 % solution was 
given subcutaneously on five days, commencing on the third day of 
fever and two days before the parasites appeared in the calf’s blood. 
The treatment was without effect. (See protocol, p. 79.) 
