60 Drug Treatment of East Coast Fever of Cattle 
Records of Cattle subjected to Drug Treatment. 
When the experiments took place in winter the animals were kept 
in stalls warmed to 60-70° C. The ticks used for infecting the animals 
were enclosed in bags fastened about the ears of the cattle. 
Blood films were prepared from the animals every day from the 
time that fever occurred. In some cases films were prepared twice 
a day or oftener. The films were stained by Giemsa’s method. To 
determine the percentage of infected red blood corpuscles it was usually 
found sufficient to count 250 corpuscles all told (infected and uninfected), 
but on some occasions 500 to 1000 were counted so as to arrive at a 
more exact result. 
Autopsies were made and the presence of typical lesions was noted 
in all cases. 
Experiment I {Calf 8). 
Treatment: (1) Congo red, 0-5 % solution, 70 c.c. injected subcutaneously on the 14th 
day. 
(2) Sodium salicylate, 10% solution + hicarhonate, 1 % in normal 
NaCl solution, 100 c.c. injected intravenously on the 21st, 22nd and 
24th day. 
(3) Mercury salicylate in 1 % solution, 5 c.c. injected intravenously on the 
29th day (too late). 
Date 
1911 
Day 
Temp, 
a.m. 
°F. 
p.rn. 
11. X. 
1 
— 
101-4 
2 
101-2 
101-8 
3 
101-4 
101-2 
4 
101-4 
101 
5 
101-2 
101-4 
6 
100-8 
101 
7 
101-8 
101-2 
8 
100-6 
101-4 
9 
101-8 
10 
102 
102 
11 
102 
12 
102 
13 
102-6 
12 infected R. appendiculatus adults (6 6 $) were placed on the 
calf 
