72 Drug Treatment of East Coast Fever of Cattle 
Experiment XII {Calf 5). 
Treatment: Quinine bihydrochloride, 55-60 grains dissolved in 25 c.c. of water, injected 
subcutaneously at 11 a.m. on 14 successive days. (Prepared as 5 grain 
tabloids.) 
Date Day Temp. ° F. 
1911 mean M. & E. 
25. IV. 1 101-2 
2 101-4 
3 101 
4 101-5 
5 101-2 
6 101-8 
7 102-3 
8 101-8 
9 101-2 
10 101-3 
11 100-6 
12 101 
13 101-5 
14 101-6 
15 101 
16 102 
17 102-1 
18 102 
19 101-5 
20 102-1 
21 101 
22 100-6 
23 101-5 
24 102-1 
25 101-3 
26 101-2 
27 101-4 
12 infected i?. appendiculatus adults (6 6 $) were placed on the calf 
Note : it is not clear which lot of ticks produced infection, 
possibly it may have heen one of those following 
16 infected B. appendiculatus nymphs were placed on the calf 
S» >5 
some 
some 
99 . 99 
99 99 
99 99 
28 
29 
30 
31 
32 
33 
34 
35 
36 
37 
38 
39 
Temp. °F. 
a.m. p.m. 
103 Transitory febrile rise 
104-4 
104-6 
101-8 
101-4 
102-2 
100-2 
102-2 
100-6 
101-6 
100-6 
101-4 
101-8 
101-6 
100-8 
101-4 
100-1 
101 
101 
101-G 
