S. O. Yoshida 
221 
Abundance of the tvorms. At autopsy, a considerable number of 
the parasites were found not only in the subcutaneous fat, and 
muscles, but in the walls of the visceral organs including the alimentary 
canal, mesentery, kidney, lung, and heart, and a few were even 
encountered in the ventricle of the brain. The worms were not 
present in the spinal cord, the cavities of the heart, and in the orbit. 
The parasites were uniformly so abundant that we could not cut any 
portion of the tissues without injuring some of the worms. Fig. 3 
represents a piece of muscle taken from the patient’s back and showing 
many worm capsrdes on its surface. The number of the parasites 
in the whole body is of course innumerable. In my specimen of muscle 
from the lumbar region, I can easily count 20-25 capsules in every 
3 cm. square. We found rather fewer worms in the subcutaneous 
tissues of the head. It will be easily understood that death was caused 
by the great abundance of the parasites. Most of them were in the 
encapsrded state, but some were free in the tissues. 
Capsules. The worm capsules were very widely distributed in the 
body, as mentioned above. In Case I, only the cutaneous tissues 
were examined, the muscular tissues and viscera were left untouched. 
It is reasonable to believe, however, that if the worm can divide and 
increase in number in the body, they will have infested the internal 
organs and ultimately have caused the death of the patient. We can¬ 
not, however, supply any further information regarding the subsequent 
history of Case I, because the patient left the University Hospital. 
In Case I, the infested tissues—subcutaneous, chorion, and connective 
tissue—were greatly thickened, while in Case II there was no remarkable 
change in the infested tissues. 
The size of the capsules varies greatly according to the nature of 
the tissue, in which they occur; some are small and globular and 
measure about 1 mm. in diameter, whilst the largest measure 
16 X 5 mm. ; the capsules commonly measure 3-6 mm. in length 
and breadth. The large and the small capsules do not occur in any 
special localities ; they were found mixed together in all portions of 
tissues. The capsules are spherical, ovoid or elongated in shape, 
the ovoid form being the most common. Figs. 1 (w, m, o, p, and q) 
and 2 (A) represent various sizes and shapes of capsules. Each capsule 
is either isolated in the tissues or connected with others, and usually 
contains only one parasite, but sometimes two or more are found in it. 
In the fresh state it was easy to remove the capsules from the sur¬ 
rounding tissues. The wall of the capsules was yellowish-white in 
