WORKS ON GLANDERS. 
597 
United Provinces, published a work in which he considered glan¬ 
ders as a disease of the humours; and compared the chancres of the 
pituitary membrane with those of the urethra in gonorrhaea, ot 
which the cause was local. As an external treatment, he recom¬ 
mended fumigations and injections. Internally lie prescribed 
sudorifics, mercurial purgatives, and diluents. He considered the 
contagiousness of the malady problematical. There were nume¬ 
rous examples of security in the most highly infected atmosphere; 
but these were not to be implicitly confided in. 
M. Brugnone, Veterinary Professor at the University of Turin, 
observed in 1774, that Vegetiushad accurately described glanders 
under the name of projiuvium atticum , and he compared the 
chancres of the pituitary membrane with venereal ulcers. He 
cautioned those who examined the horse not to confound the ter¬ 
mination of the lachrymal duct with a glanderous chancre, which 
was very often done, both at Paris and Turin. He relates as a 
reason for this caution, that in 1772 there were a great many 
glandered horses in some of the regiments of cavalry ; and that 
the farriers, who were directed to visit them in order that the sound 
horses might be separated from the diseased, gave in a most 
fearful report, for they declared that every horse was glandered, 
regarding this orifice as a true chancre. 
M. Brugnone affirms that there is sometimes, in the interior of 
the nose, an obstinate foetid ulcer called ozena, and which may, 
in process of time, degenerate into glanders; he consequently 
does not adopt the opinion of Lafosse, w r ho regards ozena as the 
veritable glanders. 
M. Paulet, in 1775, in the second volume of his Researches 
on Epizootic Maladies, very properly observes, that before under¬ 
taking the cure of any glandered horse he should be separated 
from the sound ones, for there can be no risk in considering all 
the species of mange as contagious, while there may be very 
great risk in holding the contrary opinion. 
In 1779, M. Chabert published a memoir on glanders. He 
considered ammonia, diluted with simple water, or orange-flower 
water, and injected into one of the jugulars, as the most effica¬ 
cious means that could be adopted, and especially in large fat 
horses of a lax texture. Domingo Royo had recommended the 
same mode of treatment in 1734. 
About the end of the year 1780, the King of Denmark publish¬ 
ed an ordinance in which he commanded that his kingdom should 
be searched, and every glandered horse immediately destroyed, 
without the slightest compensation being offered to the owner. 
The carcasses were to be buried in deep trenches, and the minis¬ 
ters of justice were directed to cany the ordinance into execution 
with the strictest diligence and impartiality. 
VOL. IV. 4 M 
