224 
Tryposafrol 
Guinea- 
pig 
No. Weight 
12 250 g. 
13 245 g. 
14 235 g. 
(Novo-tryposafrol.) 
Occurrence of trypanosomes in the blood on succeeding days, etc. 
1 tryp. per film on 6th day; 2 on 7th; 1 per 4 fields on 9th; 0 on 13th 
and 15th; 1 per 10 fields on 18th; on the 19th-23rd there were 2, 
5, 20, 10 and 15 per field respectively; numerous on 26th. Death 
on 26th day. 
1 tryp. per film on 6th day; on the 7th, 9th, 13th and 15th there were 
1, 2, 1 and 2 per field respectively; 25 per field on 18th. Death on 
18th day. 
1 tryp. per film on 6th day; 0 on 7th; 1 per 10 fields on 9th; 0 on 
13th-14tli; 1 per 2 fields on 18th; 1 per 10 fields on 19th. Death 
on 19th day. 
15 225 g. 1 tryp. per film on 6th day; 2 on 7th; 1 per 3 fields on 8th; the 
animal showed paralysis in the hind quarters and acute diarrhoea 
before. Death on 8th day. 
(Tryposafrol.) 
16 
320 g. 
1 tryp. per film on 6th day; 
fields on 13th; 5 on 15th; 
19th day. 
17 
355 g. 
2 tryps. per film on 6th day; 
8th. Death on 8tli day. 
18 
245 g. 
1 tryp. per film on 6th day; 
paralysis of hind quarters. 
19 
255 g. 
2 tryps. per film on 5th day; 
8th day. 
1 per field on 7th; 0 on 9th; 1 per 10 
15 on 18th; many on 19th. Death on 
1 per 10 fields on 7th; 1 per 2 fields on 
1 per 10 fields on 7th, the animal shows 
Death on 7th day. 
1 per field on 6th; 5 on 7tli. Death on 
Control Experiments. 
Three guinea-pigs (D, E and F) served as controls to the treated 
guinea-pigs Nos. 12-19, being inoculated on the same day and with the 
same blood; the animals received no treatment. 
Guinea- 
P’g 
Weight 
D 
360 g. 
E 
230 g. 
F 
225 g. 
Occurrence of trypanosomes in the blood on succeeding days, etc. 
1 tryp. per film on 5th day; 1 per 4 fields on 6th; 1 per 5 fields on 
7th; 15 per field on 12th; on 14th-19th there were 1, 10, 5, 20, 15, 
10 per field respectively; numerous on 25th. Death on 25th day. 
1 tryp. per film on 5th day; 6 on 6th; on the 7th, 12th, 14th, 17th- 
20th days there were 5, 20, 15, 2, 15, 40 and 25 per field respec¬ 
tively; numerous on 22nd, 25th and 27th. Death on 27tli day. 
1 tryp. per film on 5th day; 1 per 6 fields on 6th; on the 7tli, 12th, 
14th, 17th and 18th there were 5, 15, 15, 35 and 20 per field respec¬ 
tively; numerous on 19th, 20th and 22nd. Death on 25th day. 
