30 
The Working Group on Revision of the Guidelines at its January 21, 1983, 
meeting reccrmended incorporation into the Guidelines of the Physical 
Containment Recanmendations . Dr. Nightingale pointed out that editorial 
modifications to revise and update sections of the Physical Containment 
Recanmendations will be necessary if the RAC recommends this action. These 
minor editorial changes will reflect the modifications introduced into 
the Guidelines since the Recommendations were published in April 1980. 
Dr. Nightingale noted that one comment on the proposed action was received 
(tab lllO ) : Dr. Irving Johnson of Eli Lilly and Oonpany "does not see a 
particular need to incorporate" the Recommendations into the Guidelines. 
Dr. Levine asked the industrial representatives present at the meeting to 
comment on the proposal. Dr. Harvey Price of the Industrial Biotechnology 
Association (IBA) said the IRA did not adopt a formal position regarding 
Dr. Waitz' proposal. Most IBA member companies support the proposal; 
however, same member companies disagree. 
Mr. Bernard Mlynczak of Monsanto Corporation said Monsanto complies with the 
Guidelines and the Large-Scale Recanmendations . He said Monsanto would 
comply vhether or not the Recommendations were an appendix of the Guidelines. 
Dr. Pat Fallon of Hof fman-LaRoche, Inc., concurred. Dr. Wensink thought 
university IBCs would find it convenient to have the Recanmendations as 
part of the Guidelines . 
Dr. Niqhtingale moved that the Large-Scale Recommendations be included as 
an appendix in the Guidelines, with incorporation of the editorial modifica- 
tions preposed in tab 1101/lV. Mr. Mitchell seconded the motion. 
By a vote of sixteen in favor, none opposed, and one abstention, the RAC 
recommended the Large-Scale Recommendations be incorporated into the Guidelines 
as an appendix. 
XV. FUTURE MEETING DATES 
Dr. Gartland said the next RAC meeting was scheduled for September 19, 1983. 
XVI. CLOSING REMARKS AND ADJOURNMENT 
Dr . Gartland said the terms of six RAC members would terminate on 
June 30, 1983. The members leaving the committee are: the Chairman, 
Dr. Kenneth Bems; Drs . Winston Brill; Werner Maas; Elena Nightingale; 
James Mason; and Jean Harris . Dr. Gartland awarded certificates of service 
to the retiring members . 
Dr . Perns said he had tremendously enjoyed working with the RAC committee 
and NIH staff. 
Rre meeting was adjourned at 4:45 p.n., April 11, 1983. 
I I ■ - 5 -• | 
[115] 
