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Federal Register / Vol. 49, No. 81 / Wednesday, April 25, 1984 / Notices 
III — B— 4 — b. For all experiment* involving 
whole animals and plants not covered by LU- 
B— 4-a, the appropriate containment will be 
determined by the IBC (22). 
4. A new footnote concerning Section 
III— B — 4 — b is added to Section V, 
Footnotes and Reference of Sections I- 
IV. as follows: 
22. For recombinant DNA experiment* in 
which the intent is to modify stably the 
genome of cells of a human subject see 
Section IH-A-4. 
Dated: April 17, 19B4. 
Richard M. Krause, 
Director, National Institute of A llergy and 
Infectious Diseases, National Institutes of 
Health. 
OMB's "Mandatory Information 
Requirements far Federal Assistance Program 
Announcements" (45 FR 39592) requires a 
statement concerning the official government 
programs contained in the Catalog of Federal 
Domestic Assistance. Normally NIH lists in 
its announcements the number and title of 
affected individual programs for the guidance 
of the public. Because the guidance in this 
notice covers not only virtually every NIH 
program but also essentially every federal 
research program in which DNA recombinant 
molecure techniques could be used, it has 
been determined to be not cost effective or in 
the public interest to attempt to list these 
programs. Such a list would likely require 
several additional pages. In addition, NIH 
could not be certain that every federal 
program would be included as many federal 
agencies, as well as private organizations, 
both national and international, have elected 
to follow the NIH Guidelines, in lieu of the 
individual program listing, NIH invites 
readers to direct questions to the information 
address above about whether individual 
programs listed in the Catalog of Federal 
Domestic Assistance are affected. 
|FR Doc 84-10772 Filed 4-24-84. 8:45 «m| 
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