16 
developed . The results of the outlined tests must be submitted 
for review by the IBC. Copies must also be submitted to the Plant 
Working Group of the RAC. 
"Supporting data should include the following: 
"a. total area; 
"b. geographical location(s): where, hew many locations; 
"c. plot design: for example, replication, row spacing, nature of 
border rows; 
"d. specify plant monitoring procedures: frequency; types of data 
to be obtained, including leaf, seed, fruit, or root character- 
istics; disease and insect population monitoring; 
"e. specify techniques for monitoring the vector and/or altered 
DNA; and 
"f. specify access and security measures." 
RISK ASSESSMENT WORKSHOP 
Dr. McGarrity asked Dr. Tolin for an update on the planned risk assessment 
workshop. Dr. Tolin said the workshop planned jointly by the NIH and USDA was 
to review and synthesize available scientific information. She said the NIH- 
USDA workshop should provide information to RAC in its deliberations and should 
also benefit RAC working groups such as the Working Group on Release into 
Environment. Dr. Tolin thought the workshop would focus primarily on plants 
and associated microorganisms and would most probably be similar in format to 
the workshop sponsored by the National Institute of Allergy and Infectious 
Diseases (NIAID) at Pasadena, California. 
On April 11-12, 1980, NIAID sponsored in Pasadena, California, A "Workshop on 
Reccmbinant DNA Risk Assessment." The workshop was designed to define the 
scientific issues and assess the potential risks of: (1) possible direct 
adverse effects of hormone-producing strains of E. coli K-12, and (2) the 
possible occurrence of autoantibodies or autoreactive cells due to the prod ca- 
tion of eukarotic polypeptides (including hormones) by coli K-12 should 
such strains for unexpected reasons colonize higher organisms. In order to 
address these topics, the meeting brought together scientists fron the fields 
of irrmunology, endocrinology, physiology, microbiology, infectious diseases, 
and other appropriate disciplines. The information synthesized by the workshop 
and workshop recommendations to NIAID were used to implement the NIH program 
to assess the risks of reccmbinant DNA. 
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