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Federal Register / Vol. 49, No. 179 / Thursday, September 13, 1984 / Notices 
in Appendix K-II-A through K-Il-F is 
permitted. 
4. A reference to Appendix C is added 
after the fourth sentence of Appendix K- 
I, Selection of Physical Containment 
Levels. The new sentence reads as 
follows: 
(The Pl-LS level of physical containment is 
recommended for large-scale research or 
production of viable organisms for which Pi 
is recommended at the laboratory scale such 
as those described in Appendix C.) 
OMB's "Mandatory Information 
Requirements for Federal Assistance Program 
Announcements" (45 FR 39592) requires a 
statement concerning the official government 
programs contained in the Catalog of Federal 
Domestic Assistance. Normally NIH lists in 
its announcements the number and title of 
affected individual programs for the guidance 
of the public. Because the guidance in this 
notice covers not only virtually every NIH 
program but also essentially every federal 
research program in which DNA recombinant 
molecule techniques could be used, it has 
been determined to be not cost effective or in 
the public interest to attempt to list these 
programs. Such a list would likely require 
several additional pages. In addition, NIH 
could not be certain that every federal 
program would be included as many federal 
agencies, as well as private organizations, 
both national and international, have elected 
to follow the NIH Guidelines. In lieu of the 
individual program listing, NIH invites 
readers to direct questions to the information 
address above about whether individual 
programs listed in the Catalog of Federal 
Domestic Assistance are affected. 
Dated: September 3, 1954. 
James B. Wyngaarden, M.D., 
Director, National Institutes of Health. 
|FR Doc. 64-23914 Filed 9-12-64; 6 45 »m| 
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