SYNOPSIS FOR RESEARCH INVOLVING RECOMBINANT DNA 
The following information should be provided in synoptic form 
for use by the Institutional Biosafety Committee (DNA/IBC) in reviewing 
any research proposal or activity involving recombinant DNA. It should 
be brought to the Office of Sponsored Projects (OSP) with at least one 
copy of the protocol for the DNA/IBC Chairman to evaluate at the time 
OSP is administratively checking the application. The synopsis should 
contai n : 
1. A brief description of the experiments (generally one or 
two paragraphs) including: 
(a) Objective and methods. 
(b) Statement of whether a gene library will be created. 
(c) Brief description of the genes to be cloned. Genes 
for toxins, transformation, or drug resistance should 
be described in detail. 
(d) Notation and description of the .use of DNA from Class 3, 
4 or 5 pathogens* or cells known to be infected by these 
organi sms . 
2. Statement of the host-vector system to be used. 
3. Statement of whether a deliberate effort will be made to 
obtain a peptide product in the host. 
4. Statement describing the use of large multiliter cultures. 
* See appendix B of the "Guidelines." 
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