BROOKHAVEN NATIONAL LABORATORY 
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ASSOCIATED UNIVERSITIES, INC. 
Upton, Long Island, New York 11973 
(516) 282 \ 3420 
FTS 666 x 
January 15, 1983 
Dr. William J. Gartland, Jr. 
Office of Recombinant DNA Activities 
Building 31, Room 4A52 
National Institutes of Health 
Bethesda, Maryland 20205 
Dear Bill: 
This is in answer to the Memorandum to IBC Chairpersons. 
1) No problems with revised Guidelines. 
2) 3) No large amounts of time required or spent, mostly because we have 
only straightforward requests that fall into a clearly designated category, and 
also because our nonscientific members are not stupid and do not become 
hysterical about imaginary horrors. 
4) 5) The Brookhaven IBC does adhere to the Guidelines. Nevertheless 
the majority of members seem to feel that recombinant DNA work should not 
have Guidelines, and that precautions should be taken in accordance with 
those needed for handling the organisms involved in construction of the 
recombinant DNA (i.e., "Stetten-type " Guidelines). 
6) The IBC meets on the average about once a year, since almost all 
our business can be carried on by mail. We voted to have a meeting only if 
any one IBC member felt we should have a discussion concerning a proposal. 
Usually all members have felt the issue was straightforward. 
7) Our IBC is charged only with the responsibility of dealing with 
recombinant DNA work. Brookhaven has a rather elaborate Safety and 
Environmental Protection Division. We are not a part of this Division, but 
one of our members is. 
Sincerely yours, 
Jane K. Setlow, Chairman 
Brookhaven National Laboratory IBC 
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