SCHEFUNG CORPORATION 
60 ORANCE STREET 
BLOOMFIELD, N. J. 07003 
TELEPHONE (201)429 4000 
TELEX: 138183 
CABLES SCHERING BLOOMFIELD. N J 
May 18, 1984 
Dr. William J. Gartland, Jr. 
Di rector 
Office of Recombinant DNA Activities 
Building 31, Room 3B10 
National Institutes of Health 
Bethesda, Maryland 20205 
Dear Dr. Gartland: 
With respect to the Federal Register notice of April 24, 1984 
(49FR 17682), the following comments are offered regarding the 
recommendations listed in "The Environmental Implications of Genetic 
Engineering". 
Schering Corporation is a multinational pharmaceutical company 
which uses recombinant DNA technology under contained conditions to 
produce ethical drug products. Since we do not plan to deliberately 
release genetically engineered organisms to the environment, we will 
not comment on the specifics of most of these recommendations. 
However, Schering is concerned about recommendation number 5 which 
calls upon NIH to limit the scope of its jurisdiction to NIH-sponsored 
research. We strongly disagree with this recommendation for the same 
reasons we urged RAC to vote "No" on Dr. Talbot's four questions 
concerning boundaries for NIH and RAC oversight (49 FR 696). A copy 
of my letter to you on this subject is attached for information. 
Accordingly, we urge RAC to reject recommendation number 5 and to 
continue functioning in its current mode. 
Sincerely yours. 
/tb 
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