DAVID CERNA-PHYSIOLOGICAL ACTIONS OF SPARTEINE. 
59 
Experiment XI: Took two frogs, A and B, and after both had been 
pithed their hearts were exposed. 
Heart A. 
Time, 
h. min. 
Pulse, 
p. min. 
Remarks. 
3:40 
62 
3:45 
60 
3:47 
60 
0.001 gramme of sparteine. 
3:50 
64 
3:53 
68 
3:56 
72 
Convulsive twitchings. 
3:59 
74 
4:05 
70 
Ventricular contractions marked. 
4:10 
68 
0.001 gramme of sparteine. 
4:15 
64 
Convulsions. 
4:22 
56 
Ventricular contractions vigorous. 
4:28 
48 
4:42 
32 
Prolonged diastole marked, followed by ventricular contrac¬ 
tions so vigorous as to send out apparently every drop of 
blood, the ventricular walls becoming white at each systole. 
4:52 
30 
4:5S 
24 
5:02 
24 
5:10 
20 
5:20 
16 
Diastole and systole quite marked yet. 
5:30 
8 
6:00 
— 
Heart still beating about once or twice in the minute. 
Heart B (Control experiment). 
Time, 
h. min. 
Pulse, 
p. min. 
Remarks. 
3:42 
68 
3:46 
66 
3:48 
66 
3:52 
62 
3:55 
62 
3:58 
60 
4:02 
56 
4:08 
50 
4:12 
46 
4:18 
38 
4:25 
26 
4:40 
12 
4:50 
— 
Stopped in diastole. 
