C. Strickland 
247 
counted in three successive preparations, but sometimes only two 
preparations were made. 
Cow I 
October 18 
White cells per c.mm. 
6640 
November 4 
285 
Cow II 
December 1 
4540 
„ 15 
560 
Cow III 
February 1 
3650 
„ 14 
2940 
„ 16 
2250 
Cow IV 
February 18 
15616 
24 
11070 
March 2 
6870 
„ 7 
4320 
„ 10 
1840 
There is therefore a very marked leucopenia present in East Coast 
Fever, but it is difficult to explain its pathological significance. 
This result is in marked contrast to the leucocytosis observed in a 
dog infected with Piroplasmosis. 
25.ii.1911. Day 1 
White cells per c.mnu 
7950 
5 
7900 
7 
8666 
9 
7900 
11 
7100 
13 
10000 
15 
10250 
Differential leucocyte counts. 
We counted 500 white cells, with the following results: 
Cow V 
October 19 
October 25 
October 26 
Polymorphs 
40-0 
52 
58 
Mononuclears 
31 ' 6 \ 
14-4/ 40 
43), r 
3J 46 
3L6). 
Lymphocytes 
6-8/' 
Eosinophils 
13-6 
2 
2-2 
Mast cells 
0-6 
0 
1-4 
We cannot account for the abnormal number of eosinophils early 
in the course of the disease (the cow showed Theileria on October 13), 
but it may have some significance. The marked leucopenia, it will be 
seen, is caused by a greater relative decrease of the elements other than 
polymorphs, rather contrary to what usually occurs in protozoal 
diseases. 
16—2 
