64 
actually received 2.5 cc. of the blood serum of Cruz. (For details of 
this filtration, see p. 62.) 
On September 16 there were no symptoms. 
September IT, at 7 a. m., he was found with a temperature of 39.5° 
C., with marked frontal headache, pains in the loins and calves of the 
legs. His gums w T ere slightly swollen and he had injection of the 
ocular conjunctive. The patient said that at 1 o’clock in the morning 
he felt like stretching and had a chill. The blood showed no malarial 
parasites. Urine showed a trace of albumin. 
September 18: Eyes and body jaundiced. 
The patient made a rapid recovery after a mild but definite attack 
of yellow fever. 
German Ramos (case L), aged 22, single; has always lived in the 
mountains near Puebla. He was given a careful physical examina¬ 
tion August 26. Blood and urine negative. He was brought to Vera 
Cruz August 28 and immediately placed in a mosquito-proof room, 
where he was kept under observation eighteen days, when he was 
given an injection of filtered serum, as follows: 
On September 15, at 4 p. m., he was given an injection into the 
right median basilic vein of 5 cc. of diluted serum of Marcos Cruz, 
filtered through a Pasteur-Chamberland filter B. This serum having 
been diluted with an equal volume of physiological salt solution, 
Kamos received 2.5 cc. of the serum of Cruz. (For details of this 
filtration, see the records of Marcos Cruz, page 62.) 
September 16, no change. 
September 17, at 7 a. m., his temperature was 37.3° C., and he did 
not feel at all unusual; but at 9.15 a. m. his temperature was 39.4°. 
He had frontal headache, pains in the back and calves of the legs. 
The blood was negative for malaria. 
September 18, the eyes were injected and the body jaundiced. 
Patient vomited twice. He exhibited a typical clinical picture of 
yellow fever. 
His temperature on the third day was higher than at the onset of 
the disease, which is rather unusual, and in Vera Cruz is considered 
a grave sign. It will also be noted that his febrile period, which 
lasted seven days, did not show the characteristic remission. Albu¬ 
min first appeared on the 21st and continued until the 25th, when 
examination was discontinued. 
Patient recovered. 
Guadalupe Gomez (case LI) ; born in Jalapa, aged 17, had never 
been on the coast, and states that he never had any kind of fever. He 
was physically sound when examined; blood and urine negative. He 
was brought to Yera Cruz August 28 and placed in a mosquito-proof 
room, where he was kept under observation eighteen days. 
